Sökning: WFRF:(Van Veldhuisen Dirk J.)
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Quality of life is ...
Quality of life is impaired similarly in heart failure patients with preserved and reduced ejection fraction
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- Hoekstra, Tialda (författare)
- University of Groningen
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- Lesman-Leegte, Ivonne (författare)
- University of Groningen
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- van Veldhuisen, Dirk J (författare)
- University of Groningen
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- Sanderman, Robbert (författare)
- University of Groningen
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- Jaarsma, Tiny (författare)
- Linköpings universitet,Hälsa, Aktivitet, Vård (HAV),Hälsouniversitetet
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(creator_code:org_t)
- 2014-02-18
- 2011
- Engelska.
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Ingår i: European Journal of Heart Failure. - : Oxford University Press (OUP). - 1388-9842 .- 1879-0844. ; 13:9, s. 1013-1018
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https://liu.diva-por... (primary) (Raw object)
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https://onlinelibrar...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
Ämnesord
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- Aims To compare quality of life (QoL) in heart failure (HF) patients with preserved ejection fraction (HF-PEF) and HF patients with reduced ejection fraction (HF-REF) in a well-defined HF population. less thanbrgreater than less thanbrgreater thanMethods and results Patients with HF-PEF [left ventricular ejection fraction (LVEF) andgt;= 40%] were matched by age and gender to patients with HF-REF (LVEF,40%). In the current study, we only included HF patients with a B-type natriuretic peptide level (BNP) andgt; 100 pg/mL. Quality of life was assessed by Cantrils Ladder of Life, RAND-36, and the Minnesota Living with Heart Failure questionnaire, and impairment of QoL was adjusted for by BNP as a marker for severity of HF. We examined a total of 290 HF patients, of whom 145 had HF-PEF (41% female; age 72 +/- 10; LVEF 51 +/- 8%) and 145 had HF-REF (41% female; age 73 +/- 10, LVEF 26 +/- 7%). All HF patients reported markedly low scores of QoL, both on the general and disease-specific QoL questionnaires. Quality of life between patients with HF-PEF and HF-REF did not differ significantly. When adjusting the QoL scores for BNP, an association between QoL and LVEF was not found, i.e. patients with HF-PEF and HF-REF with similar BNP levels had the same impairment in QoL. less thanbrgreater than less thanbrgreater thanConclusion Quality of life is similarly impaired in patients with HF-PEF as in HF-REF. These findings further support the need for more pharmacological and non-pharmacological studies in patients with HF-PEF.
Nyckelord
- Heart failure
- Quality of life
- Preserved ejection fraction
- Reduced ejection fraction
- B-type Natriuretic Peptide
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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