Lack of Prognostic Value of Type D Personality for Mortality in a Large Sample of Heart Failure Patients

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Coyne, James CUniversity of Groningen (author)

Lack of Prognostic Value of Type D Personality for Mortality in a Large Sample of Heart Failure Patients

Article/chapterEnglish2011

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Lippincott, Williams and Wilkins,2011
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LIBRIS-ID:oai:DiVA.org:liu-71220
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-71220URI
https://doi.org/10.1097/PSY.0b013e318227ac75DOI

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Language:English
Summary in:English

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Subject category:art swepub-publicationtype

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Background: Type D personality has been proposed as a prognostic indicator for mortality in cardiovascular disease. Most research examining this construct originates from one research group, and it is critical that the predictive value of Type D personality for adverse outcomes is independently cross-validated. This study examined its prognostic value in heart failure, relative to B-type natriuretic peptide (BNP) and depressive symptoms. Methods: We studied 706 patients with complete BNP, depressive symptom, and Type D personality and mortality data from 958 patients with heart failure enrolled after hospitalization for a multisite study of a disease management program. Multivariable models were adjusted for BNP and depression. Results: At 18 months, there were 192 deaths (27.2%). No evidence was found for a prognostic value of Type D personality in the unadjusted model (hazard ratio [HR] = 0.893, 95% confidence interval [CI] = 0.582-1.370). In contrast, BNP was significantly predictive of mortality (HR = 1.588, 95% CI = 1.391-1.812), whereas depression was not (HR = 1.011, 95% CI = 0.998-1.024). Type D was also not predictive in covariate-adjusted models (HR = 0.779, 95% CI = 0.489-1.242). Similar results were obtained when analyzing Type D as the interaction between continuous z scores of its two components, negative affectivity and social inhibition (p = .144). Conclusions: In the largest study to date, Type D does not predict mortality. Future research should construe Type D as the interaction of continuous negative affectivity and social inhibition z scores, rather than as a typology, and consider analyses replacing negative affectivity with depression.

Subject headings and genre

Type D personality
heart failure
survival
B-type natriuretic peptide
depression
MEDICINE
MEDICIN

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Jaarsma, TinyLinköpings universitet,Hälsa, Aktivitet, Vård (HAV),Hälsouniversitetet(Swepub:liu)tinja77 (author)
Luttik, Marie-LouiseUniversity of Groningen (author)
van Sonderen, EricUniversity of Groningen (author)
van Veldhuisen, Dirk JUniversity of Groningen (author)
Sanderman, RobbertUniversity of Groningen (author)
University of GroningenHälsa, Aktivitet, Vård (HAV) (creator_code:org_t)

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In:Psychosomatic Medicine: Lippincott, Williams and Wilkins73:7, s. 557-5620033-31741534-7796

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