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Influence of estrog...
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Stening, KentLinnéuniversitetet,Linköpings universitet,Cellbiologi,Hälsouniversitetet,Institutionen för hälso- och vårdvetenskap, HV
(författare)
Influence of estrogen levels on thermal perception, pain thresholds and pain tolerance : Studies on women undergoing in vitro fertilization
- Artikel/kapitelEngelska2012
Förlag, utgivningsår, omfång ...
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Elsevier BV,2012
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:liu-71869
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https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-71869URI
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https://doi.org/10.1016/j.jpain.2012.01.446DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-174563URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-20136URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:art swepub-publicationtype
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funding agencies|Swedish Research Council| 7879 |Konung Gustav V:s 80-arsfond||Health Research Council in the South-East of Sweden||Linneus University, Kalmar, Sweden||
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We examined the relationship between estrogen and pain in women undergoing in vitro fertilization (IVF). Quantitative sensory tests (QST) were performed twice during the IVF-regimen: once during hormonal down-regulation and once during hormonal upregulation. A group of healthy men and a group of women using monophasic contraceptives were also examined, to control for session-to-session effects. Among the women undergoing IVF, serum 17β-estradiol levels differed strongly between treatments as expected, and increased from 65.7 (SD = 26) pmol/l during the downregulation phase, to 5188 (SD = 2524) pmol/l during the up-regulation phase. Significant outcomes in the QST were only seen for temperature perception thresholds (1.7°C vs. 2.2°C; P = 0.003) and cold pain threshold (11.5°C vs. 14.5°C; P = 0.04). A similar change in cold pain threshold was also seen in the two control groups, however, and statistical analysis suggested that this change was due to a session-to-session effect rather than being the result of hormonal modulation. Heat pain thresholds, heat tolerance, pressure pain thresholds, and the cold pressor test showed no significant differences between sessions. These data demonstrate that pain perception and pain thresholds in healthy women show little, if any, changes even with major variations in serum estradiol levels.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Berg, GöranÖstergötlands Läns Landsting,Linköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet,Kvinnokliniken i Linköping,IKE, Linköpings universitet(Swepub:liu)gorbe09
(författare)
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Hammar, MatsÖstergötlands Läns Landsting,Linköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet,Kvinnokliniken i Linköping,IKE, Linköpings universitet(Swepub:liu)matha92
(författare)
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Voster, HeleneLinköpings universitet,Cellbiologi,Hälsouniversitetet,IKE, Linköpings universitet
(författare)
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Eriksson, OlleLinköpings universitet,Statistik,Filosofiska fakulteten,IDA, Linköpngs universitet(Swepub:liu)oller83
(författare)
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Amandusson, ÅsaUppsala universitet,Linköpings universitet,Cellbiologi,Hälsouniversitetet,Klinisk neurofysiologi,Avd. för Neurovetenskap, Uppsala universitet(Swepub:uu)asaam531
(författare)
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Blomqvist, AndersLinköpings universitet,Cellbiologi,Hälsouniversitetet,IKE, Linköpings universitet(Swepub:liu)andbl47
(författare)
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Linköpings universitetCellbiologi
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Pain: Elsevier BV13:5, s. 459-4661526-59001528-8447
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