Search: id:"swepub:oai:DiVA.org:liu-73942" >
Principles of Growt...
-
Bang, Peter,1959-Karolinska Institute and University Hospital
(author)
Principles of Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children with Idiopathic Short Stature
- Article/chapterEnglish2011
Publisher, publication year, extent ...
-
2011-09-07
-
S. Karger AG,2011
-
printrdacarrier
Numbers
-
LIBRIS-ID:oai:DiVA.org:liu-73942
-
https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-73942URI
-
https://doi.org/10.1159/000330148DOI
-
http://kipublications.ki.se/Default.aspx?queryparsed=id:123249778URI
Supplementary language notes
-
Language:English
-
Summary in:English
Part of subdatabase
Classification
-
Subject category:ref swepub-contenttype
-
Subject category:art swepub-publicationtype
Notes
-
Until recently, growth hormone (GH) was the only treatment available to improve growth rate in short, prepubertal children. Insulinlike growth factor I (IGF-I) is now approved in the United States and the European Union for treatment of short stature in children with severe primary IGF-I deficiency, a condition characterized by unresponsiveness to GH in IGF-I-producing tissues. This has increased the focus on the growth response to GH therapy in short children treated according to current recommendations. In particular, children with idiopathic short stature (ISS) may have some degree of GH insensitivity that decreases their response to GH treatment. This minireview discusses data on the response to GH treatment in patients with ISS and recent studies on the use of IGF-I in subgroups of patients with ISS. The rationale for future combination treatment with GH plus IGF-I is also discussed.
Added entries (persons, corporate bodies, meetings, titles ...)
-
Karolinska Institute and University Hospital
(creator_code:org_t)
Related titles
-
In:HORMONE RESEARCH IN PAEDIATRICS: S. Karger AG76:s3, s. 24-261663-28181663-2826
Internet link
Find in a library
To the university's database