id:"swepub:oai:DiVA.org:liu-75271"
Sökning: id:"swepub:oai:DiVA.org:liu-75271" > Cost analysis of re...
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
- Alström, UlricaUppsala universitet,Anestesiologi och intensivvård,University of Uppsala Hospital (författare)
Cost analysis of re-exploration for bleeding after coronary artery bypass graft surgery
- Artikel/kapitelEngelska2012
Förlag, utgivningsår, omfång ...
- Oxford University Press (OUP): Policy B,2012
- printrdacarrier
Nummerbeteckningar
- LIBRIS-ID:oai:DiVA.org:liu-75271
- https://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-75271URI
- https://doi.org/10.1093/bja/aer391DOI
- https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-165128URI
Kompletterande språkuppgifter
- Språk:engelska
- Sammanfattning på:engelska
Ingår i deldatabas
- SwePubSwePub
Klassifikation
Anmärkningar
- Funding Agencies|Departments of Cardiovascular Surgery and Anaesthesiology at the University Hospital in Uppsala||Departments of Cardiovascular Surgery and Anaesthesiology at the University Hospital in Orebro||Departments of Cardiovascular Surgery and Anaesthesiology at the University Hospital in Linkoping||Centre for Medical Technology Assessment Department, Linkoping University, Sweden||
- Background. Re-exploration for bleeding after cardiac surgery is an indicator of substantial haemorrhage and is associated with increased hospital resource utilization. This study aimed to analyse the costs of re-exploration and estimate the costs of haemostatic prophylaxis. less thanbrgreater than less thanbrgreater thanMethods. A total of 4232 patients underwent isolated, first-time, coronary artery bypass graft (CABG) surgery during 2005-8. Each patient re-explored for bleeding (n = 127) was matched with two controls not requiring re-exploration (n = 254). Cost analysis was based on resource utilization from completion of CABG until discharge. A mean cost per patient for re-exploration was calculated. Based on this, the net cost of prophylactic treatment with haemostatic drugs for preventing re-exploration was calculated. less thanbrgreater than less thanbrgreater thanResults. Patients undergoing re-exploration had higher exposure to clopidogrel before operation, prolonged stays in the intensive care unit, and more blood transfusions than controls. The mean incremental cost for re-exploration was (sic)6290 [95% confidence interval (CI) (sic)3408-(sic)9173] per patient, of which 48% [(sic)3001 (95% CI (sic)249-(sic)2147)] was due to prolonged stay, 31% [(sic)1928 (95% CI (sic)1710-(sic)2147)] to the cost of surgery/anaesthesia, 20% [(sic)1261 (95% CI (sic)1145-(sic)1378)] to the increased number of blood transfusions, and andlt;2% [(sic)100 (95% CI (sic)39-(sic)161)] to the cost of haemostatic drugs. A cost model, at an estimated 50% efficacy for recombinant activated clotting factor VIIa and a 50% expected risk for re-exploration without prophylaxis, demonstrated that to be cost neutral, prophylaxis of four patients needed to result in one avoided re-exploration. less thanbrgreater than less thanbrgreater thanConclusions. The resource utilization costs were substantially higher in patients requiring re-exploration for bleeding. From a strict cost-effectiveness perspective, clinical interventions to prevent haemorrhage might be underutilized.
Ämnesord och genrebeteckningar
- bleeding
- cardiac surgery
- cost analysis
- re-operation
- MEDICINE
- MEDICIN
Biuppslag (personer, institutioner, konferenser, titlar ...)
- Levin, Lars-ÅkeLinköpings universitet,Utvärdering och hälsoekonomi,Hälsouniversitetet(Swepub:liu)larle77 (författare)
- Ståhle, ElisabethUppsala universitet,Thoraxkirurgi,Uppsala kliniska forskningscentrum (UCR),University of Uppsala Hospital(Swepub:uu)elsta102 (författare)
- Svedjeholm, RolfÖstergötlands Läns Landsting,Linköpings universitet,Thoraxkirurgi,Hälsouniversitetet,Thorax-kärlkliniken i Östergötland(Swepub:liu)rolsv84 (författare)
- Friberg, OÖrebro University Hospital (författare)
- Uppsala universitetAnestesiologi och intensivvård (creator_code:org_t)
Sammanhörande titlar
- Ingår i:British Journal of Anaesthesia: Oxford University Press (OUP): Policy B108:2, s. 216-2220007-09121471-6771
Internetlänk
Hitta via bibliotek
- British Journal of Anaesthesia (Sök värdpublikationen i LIBRIS)
Till lärosätets databas
- 1 av 1
- Föregående post
- Nästa post
- Till träfflistan
Hitta mer i SwePub
- Av författaren/redakt...
- Alström, Ulrica
- Levin, Lars-Åke
- Ståhle, Elisabet ...
- Svedjeholm, Rolf
- Friberg, O
- Artiklar i publikationen
- British Journal ...
- Av lärosätet
- Linköpings universitet
- Uppsala universitet
Sök utanför SwePub
- Sök vidare i:
- Google Book Search
- Google Scholar
Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.
- Copyright © LIBRIS - Nationella bibliotekssystem
- LIBRIS.kb.se
