Search: L773:1751 9918 OR L773:1878 0210
> (2010-2014) >
Circadian blood pre...
Circadian blood pressure variation in patients with type 2 diabetes - relationship to macro- and microvascular subclinical organ damage
-
- Jennersjö, Pär E. (author)
- Östergötlands Läns Landsting,Linköpings universitet,Allmänmedicin,Hälsouniversitetet,Primärvården i västra länsdelen
-
- Wijkman, Magnus (author)
- Linköpings universitet,Internmedicin,Hälsouniversitetet
-
- Wiréhn, Ann-Britt (author)
- Östergötlands Läns Landsting,Forsknings- och utvecklingsenheten för Närsjukvården i Östergötland
-
show more...
-
- Länne, Toste (author)
- Östergötlands Läns Landsting,Linköpings universitet,Fysiologi,Hälsouniversitetet,Thorax-kärlkliniken i Östergötland
-
- Engvall, Jan (author)
- Östergötlands Läns Landsting,Linköpings universitet,Klinisk fysiologi,Hälsouniversitetet,Fysiologiska kliniken US
-
- Nyström, Fredrik H. (author)
- Östergötlands Läns Landsting,Linköpings universitet,Internmedicin,Hälsouniversitetet,Endokrin- och magtarmmedicinska kliniken US
-
- Östgren, Carl Johan (author)
- Östergötlands Läns Landsting,Linköpings universitet,Allmänmedicin,Hälsouniversitetet,Primärvården i västra länsdelen
-
show less...
-
(creator_code:org_t)
- Elsevier, 2011
- 2011
- English.
-
In: Primary Care Diabetes. - : Elsevier. - 1751-9918 .- 1878-0210. ; 5:3, s. 167-173
- Related links:
-
https://urn.kb.se/re...
-
show more...
-
https://doi.org/10.1...
-
show less...
Abstract
Subject headings
Close
- AimsTo explore the association between nocturnal blood pressure (BP) dipper status and macro- and microvascular organ damage in type 2 diabetes.MethodsCross-sectional data from 663 patients with type 2 diabetes, aged 55–66 years, were analysed. Nurses measured office BP and ambulatory BP during 24 h. Individuals with ≥10% difference in nocturnal systolic blood pressure (SBP) relative to daytime values were defined as dippers. Non-dippers were defined as <10% nocturnal decrease in SBP. Estimated glomerular filtration rate (GFR) was calculated and microalbuminuria was measured by albumin:creatinine ratio (ACR). Aortic pulse wave velocity (PWV) was measured with applanation tonometry over the carotid and femoral arteries.ResultsWe identified 433 dippers and 230 subjects with a nocturnal non-dipping pattern. Nocturnal SBP dipping was independently of office SBP associated with decreased PWV (p = 0.008), lower ACR (p = 0.001) and NT-proBNP (p = 0.001) and increased GFR (p < 0.001).ConclusionsWe conclude that diurnal BP variation provides further information about early macro- and microvascular subclinical organ damage that goes beyond standardized office BP measurements in patients with type 2 diabetes.
Keyword
- Type 2 diabetes mellitus ambulatory blood pressure arterial stiffness microalbuminuria diurnal blood pressure variation
Publication and Content Type
- ref (subject category)
- art (subject category)
Find in a library
To the university's database