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Lower risk of stent...
Lower risk of stent thrombosis and restenosis with unrestricted use of onew-generation drug-eluting stents: a report from the nationwide Swedish Coronary Angiography and Angioplasty Registry (SCAAR)
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- Sarno, Giovanna (författare)
- Uppsala universitet,Uppsala kliniska forskningscentrum (UCR),kardiologi,Uppsala University
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- Lagerqvist, Bo (författare)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Kardiologi,Uppsala University
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- Fröbert, Ole (författare)
- Örebro University Hospital
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- Nilsson, Johan (författare)
- Umeå universitet,Kardiologi,Umeå University Hospital
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- Olivecrona, Göran (författare)
- Lund University,Lunds universitet,Kardiologi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Cardiology,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,University of Lund Hospital
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- Omerovic, Elmir, 1968 (författare)
- Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine,University of Gothenburg
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- Saleh, Nawzad (författare)
- Karolinska Institutet,Karolinska University Hospital
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- Venetzanos, Dimitris (författare)
- Östergötlands Läns Landsting,Kardiologiska kliniken US
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- James, Stefan, 1964- (författare)
- Uppsala universitet,Institutionen för medicinska vetenskaper,Uppsala kliniska forskningscentrum (UCR),Kardiologi,Uppsala University
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(creator_code:org_t)
- 2012-01-09
- 2012
- Engelska.
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Ingår i: European Heart Journal. - : Oxford University Press (OUP): Policy B. - 0195-668X .- 1522-9645. ; 33:5, s. 606-613
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http://dx.doi.org/10...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://lup.lub.lu.s...
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http://kipublication...
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https://gup.ub.gu.se...
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https://urn.kb.se/re...
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https://urn.kb.se/re...
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Abstract
Ämnesord
Stäng
- To compare the long-term outcome after percutaneous coronary intervention with onew-generation drug-eluting stents (n-DES) to oolder generation DES (o-DES), and bare-metal stents (BMS) in a real-world population. less thanbrgreater than less thanbrgreater thanWe evaluated 94 384 consecutive stent implantations (BMS, n 64 631; o-DES, n 19 202; n-DES, n 10 551) in Sweden from November 2006 to October 2010. All cases of definite stent thrombosis (ST) and restenosis were documented in the Swedish Coronary Angiography and Angioplasty Registry (SCAAR). Older generation DES were classified as: Cypher and Cypher Select (Cordis Corporation, Miami, FL, USA), Taxus Express and Taxus Libert (Boston Scientific Corporation), and Endeavor (Medtronic Inc.) and n-DES as: Endeavor Resolute (Medtronic Inc.), XienceV, Xience Prime (Abbott Laboratories) and Promus, Promus Element (Boston Scientific Corporation). The Cox regression analyses unadjusted and adjusted for clinical and angiographic covariates showed a statistically significant lower risk of restenosis in n-DES compared with BMS [adjusted hazard ratio (HR) 0.29; 95 confidence interval (CI): 0.250.33] and o-DES (HR 0.62; 95 CI: 0.530.72). A lower risk of definite ST was found in n-DES compared with BMS (HR 0.38; 95 CI: 0.280.52) and o-DES (HR, 0.57; 95 CI: 0.410.79). The risk of death was significantly lower in n-DES compared with o-DES (adjusted HR: 0.77; 95 CI: 0.630.95) and BMS (adjusted HR: 0.55; 95 CI: 0.460.67). less thanbrgreater than less thanbrgreater thanPercutaneous coronary intervention with n-DES is associated with a 38 lower risk of clinically meaningful restenosis, a 43 lower risk of definite ST, and a 23 lower risk of death compared with o-DES in this observational study from a large real-world population.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Kardiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cardiac and Cardiovascular Systems (hsv//eng)
Nyckelord
- DES
- Stent thrombosis
- TECHNOLOGY
- TEKNIKVETENSKAP
- Stent thrombosis
- DES
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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Sarno, Giovanna
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Lagerqvist, Bo
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Fröbert, Ole
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Nilsson, Johan
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Olivecrona, Göra ...
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Omerovic, Elmir, ...
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Saleh, Nawzad
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Venetzanos, Dimi ...
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James, Stefan, 1 ...
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