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Finding the founder...
Finding the founder of Stockholm - A kinship study based on Y-chromosomal, autosomal and mitochondrial DNA
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- Malmström, Helena (författare)
- Uppsala universitet,Evolutionsbiologi,Department of Evolutionary Biology, Uppsala
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- Vretemark, Maria (författare)
- Vastergotlands Museum
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- Tillmar, Andreas (författare)
- National Board for Forensic Medicine
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- Brandström Durling, Mikael (författare)
- Swedish University of Agricultural Sciences,Sveriges lantbruksuniversitet,Institutionen för skoglig mykologi och patologi,Department of Forest Mycology and Pathology,Swedish University of Agriculture Science
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- Skoglund, Pontus (författare)
- Uppsala universitet,Evolutionsbiologi,Department of Evolutionary Biology, Uppsala
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- Gilbert, M Thomas P (författare)
- University of Copenhagen
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- Holmlund, Gunilla (författare)
- Linköpings universitet,Institutionen för klinisk och experimentell medicin,Hälsouniversitetet
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- Götherström, Anders (författare)
- Uppsala universitet,Evolutionsbiologi,Department of Evolutionary Biology, Uppsala
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Willerslev, Eske (författare)
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(creator_code:org_t)
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- Elsevier, 2012
- 2012
- Engelska.
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Ingår i: Annals of Anatomy. - : Elsevier. - 0940-9602 .- 1618-0402. ; 194:1, s. 138-145
- Relaterad länk:
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https://urn.kb.se/re...
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://res.slu.se/i...
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Abstract
Ämnesord
Stäng
- Historical records claim that Birger Magnusson (died 1266), famous regent of Sweden and the founder of Stockholm, was buried in Varnhem Abbey in Vastergotland. After being lost for centuries, his putative grave was rediscovered during restoration work in the 1920s. Morphological analyses of the three individuals in the grave concluded that the older male, the female and the younger male found in the grave were likely to be Birger, his second wife Mechtild of Holstein and his son Erik from a previous marriage. More recent evaluations of the data from the 1920s seriously questioned these conclusions, ultimately leading to the reopening and reexamination of the grave in 2002. Ancient DNA-analyses were performed to investigate if the relationship between the three individuals matched what we would expect if the individuals were Birger, Erik and Mechtild. We used pyrosequencing of Y-chromosomal and autosomal SNPs and compared the results with haplogroup frequencies of modern Swedes to investigate paternal relations. Possible maternal kinship was investigated by deep FLX-sequencing of overlapping mtDNA amplicons. The authenticity of the sequences was examined using data from independent extractions, massive clonal data, the c-statistics, and real-time quantitative data. We show that the males carry the same Y-chromosomal haplogroup and thus we cannot reject a father-son type of relation. Further, as shown by the mtDNA analyses, none of the individuals are maternally related. We conclude that the graves indeed belong to Birger, Erik and Mechtild, or to three individuals with the exact same kind of biological relatedness.
Ämnesord
- NATURVETENSKAP -- Biologi -- Evolutionsbiologi (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Evolutionary Biology (hsv//eng)
- HUMANIORA -- Historia och arkeologi -- Arkeologi (hsv//swe)
- HUMANITIES -- History and Archaeology -- Archaeology (hsv//eng)
- NATURVETENSKAP -- Biologi -- Genetik (hsv//swe)
- NATURAL SCIENCES -- Biological Sciences -- Genetics (hsv//eng)
- HUMANIORA -- Historia och arkeologi -- Historia (hsv//swe)
- HUMANITIES -- History and Archaeology -- History (hsv//eng)
Nyckelord
- Birger jarl
- Ancient DNA
- SNPs
- HVS1
- FLX sequencing
- MEDICINE
- MEDICIN
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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