Cancer stem cell markers in common cancers - therapeutic implications

Klonisch, ThomasDepartment of Human Anatomy and Cell Sciences, Winnipeg, Canada (författare)

Rapid advances in the cancer stem cell (CSC) field have provided cause for optimism for the development of more reliable cancer therapies in the future. Strategies aimed at efficient targeting of CSCs are becoming important for monitoring the progress of cancer therapy and for evaluating new therapeutic approaches. Here, we characterize and compare the specific markers that have been found to be present on stem cells, cancer cells and CSCs in selected tissues (colon, breast, liver, pancreas and prostate). We then discuss future directions of this intriguing new research field in the context of new diagnostic and therapeutic opportunities.

Wiechec, EmiliaManitoba Institute of Cell Biology, CancerCare Manitoba; Department of Human Genetics, University of Aarhus, Aarhus, Denmark(Swepub:liu)emiwi22 (författare)
Hombach-Klonisch, SabineDepartment of Human Anatomy and Cell Science, University of Manitoba, Winnipeg, R3E 0W3, MB, Canada (författare)
Ande, Sudharsana R.Manitoba Institute of Cell Biology, CancerCare Manitoba, Winnipeg, R3E 0V9, MB, Canada; Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, R3E 0W3, MB, Canada (författare)
Wesselborg, SebastianDepartment of Internal Medicine I, University of Tübingen, D-72076 Tübingen, Germany (författare)
Schulze-Osthoff, KlausInterfaculty Institute for Biochemistry, University of Tübingen, Germany (författare)
Los, Marek JanUniversity of Manitoba, Winnipeg, Canada(Swepub:liu)marlo14 (författare)
Department of Human Anatomy and Cell Sciences, Winnipeg, CanadaManitoba Institute of Cell Biology, CancerCare Manitoba; Department of Human Genetics, University of Aarhus, Aarhus, Denmark (creator_code:org_t)

Ingår i:Trends in Molecular Medicine: Elsevier14:10, s. 450-4601471-49141471-499X

Av författaren/redakt...: Klonisch, Thomas; Wiechec, Emilia; Hombach-Klonisch ...; Ande, Sudharsana ...; Wesselborg, Seba ...; Schulze-Osthoff, ...; visa fler...; Los, Marek Jan; visa färre...

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