Hybrid Semiconducting Polymer Dot-Quantum Dot with Narrow-Band Emission, Near-Infrared Fluorescence, and High Brightness

Chan, Yang-HsiangDepartment of Chemistry, University of Washington, Seattle, USA (author)

This communication describes a new class of semiconducting polymer nanoparticle–quantum dot hybrid with high brightness, narrow emission, near-IR fluorescence, and excellent cellular targeting capability. Using this approach, we circumvented the current difficulty with obtaining narrow-band-emitting and near-IR-fluorescing semiconducting polymer nanoparticles while combining the advantages of both semiconducting polymer nanoparticles and quantum dots. We further demonstrated the use of this new class of hybrid nanomaterial for effective and specific cellular and subcellular labeling without any noticeable nonspecific binding. This hybrid nanomaterial is anticipated to find use in a variety of in vitro and in vivo biological applications.

Ye, FangmaoDepartment of Chemistry, University of Washington, Seattle, USA (author)
Gallina, Maria ElenaDepartment of Chemistry, University of Washington, Seattle, USA (author)
Zhang, XuanjunDepartment of Chemistry, University of Washington, Seattle, USA(Swepub:liu)xuazh91 (author)
Jin, YuhuiDepartment of Chemistry, University of Washington, Seattle, USA (author)
Wu, I-CheDepartment of Chemistry, University of Washington, Seattle, USA (author)
Chiu, Daniel TDepartment of Chemistry, University of Washington, Seattle, USA (author)
Department of Chemistry, University of Washington, Seattle, USA (creator_code:org_t)

In:Journal of the American Chemical Society: American Chemical Society (ACS)134:17, s. 7309-73120002-78631520-5126

By the author/editor: Chan, Yang-Hsian ...; Ye, Fangmao; Gallina, Maria E ...; Zhang, Xuanjun; Jin, Yuhui; Wu, I-Che; show more...; Chiu, Daniel T; show less...

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