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Sökning: (LAR1:liu) srt2:(2010-2013) pers:(Sydsjö Gunilla) > Leptin and adiponec...

Leptin and adiponectin in cord blood from children of normal weight, overweight and obese mothers

Brynhildsen, Jan (författare)
Östergötlands Läns Landsting,Linköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet,Kvinnokliniken i Linköping,Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences; Linköping University, Linköping, Sweden; Department of Obstetrics and Gynaecology in Linköping, County Council of Östergötland, Linköping, Sweden
Sydsjö, Gunilla (författare)
Östergötlands Läns Landsting,Linköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet,Kvinnokliniken i Linköping,Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences; Linköping University, Linköping, Sweden; Department of Obstetrics and Gynaecology in Linköping, County Council of Östergötland, Linköping, Sweden
Blomberg, Marie (författare)
Östergötlands Läns Landsting,Linköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet,Kvinnokliniken i Linköping,Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences; Linköping University, Linköping, Sweden; Department of Obstetrics and Gynaecology in Linköping, County Council of Östergötland, Linköping, Sweden
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Claesson, Ing-Marie (författare)
Östergötlands Läns Landsting,Linköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet,Kvinnokliniken i Linköping,Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences; Linköping University, Linköping, Sweden; Department of Obstetrics and Gynaecology in Linköping, County Council of Östergötland, Linköping, Sweden
Theodorsson, Elvar (författare)
Östergötlands Läns Landsting,Linköpings universitet,Klinisk kemi,Hälsouniversitetet,Division of Laboratory, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden
Nyström, Fredrik H. (författare)
Östergötlands Läns Landsting,Linköpings universitet,Avdelningen för kardiovaskulär medicin,Hälsouniversitetet,Endokrinmedicinska kliniken,Division of Internal Medicine, Department of Medical and Health Sciences, Faculty of Health Sciences, Linköping University, Linköping, Sweden
Sydsjö, Adam (författare)
Östergötlands Läns Landsting,Linköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet,Kvinnokliniken i Linköping,Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences; Linköping University, Linköping, Sweden; Department of Obstetrics and Gynaecology in Linköping, County Council of Östergötland, Linköping, Sweden
Josefsson, Ann (författare)
Östergötlands Läns Landsting,Linköpings universitet,Obstetrik och gynekologi,Hälsouniversitetet,Kvinnokliniken i Linköping,Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences; Linköping University, Linköping, Sweden; Department of Obstetrics and Gynaecology in Linköping, County Council of Östergötland, Linköping, Sweden
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 (creator_code:org_t)
2013-03-06
2013
Engelska.
Ingår i: Acta Paediatrica. - : Wiley-Blackwell. - 0803-5253 .- 1651-2227. ; 102:6, s. 620-624
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • Aim To study cord blood concentrations of adiponectin and leptin in children born by normal weight, overweight and obese mothers and to study these parameters in relation to a weight gain intervention programme for obese mothers. Methods Ten millilitre cord blood was collected and analysed for leptin and adiponectin concentrations in children with gestational age andgt;37weeks born by 60 normal weight, 45 overweight and 145 obese mothers. 82 obese mothers took part in a weight gain intervention programme. Results Concentrations of leptin and adiponectin were higher in cord blood from children of overweight and obese mothers compared with children of normal weight mothers (leptin: Md 13.2, 30, 3 and 90.2ng/mL respectively, pandlt;0.001; adiponectin 35.9, 205.4, 213.8ng/L pandlt;0.001). No differences were found between overweight and obese mothers. The weight gain intervention programme for obese pregnant women had significant effects on the weight gain during pregnancy but had no effects on cord blood serum concentrations of leptin and adiponectin. Conclusion Cord blood leptin and adiponectin concentrations were higher in children born by overweight or obese women compared with children of normal weight mothers. A weight gain intervention programme for obese pregnant women did not affect these results. Intrauterine exposition to high concentrations of leptin and adiponectin may play a role in weight development later in life.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Pediatrik (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Pediatrics (hsv//eng)

Nyckelord

Adiponectin
Leptin
Obesity
Umbilical cord
MEDICINE
MEDICIN

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