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Achievement of lipo...
Achievement of lipoprotein goals among patients with metabolic syndrome at high cardiovascular risk across Europe. The EURIKA study.
- Article/chapterEnglish2013
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Elsevier BV,2013
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LIBRIS-ID:oai:DiVA.org:lnu-21841
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https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-21841URI
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https://doi.org/10.1016/j.ijcard.2011.10.094DOI
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
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OBJECTIVE: To examine for the first time the achievement of lipoprotein treatment goals in patients with metabolic syndrome and lipid abnormalities who are at elevated cardiovascular risk in Europe. METHODS: Cross-sectional study conducted in 2009-2010 in 12 European countries among outpatients aged ≥50years free of clinical cardiovascular disease. We assessed achievement of American Diabetes Association/American College of Cardiology lipid treatment goals in those with metabolic syndrome at highest risk (diabetes plus ≥1 additional major cardiovascular risk factor beyond lipid abnormalities) or high risk (no diabetes but ≥2 additional major cardiovascular risk factors). RESULTS: Among 1431 highest-risk patients, 64.6% (between-country range [BCR] 40-84.5%) were on lipid-lowering medication. Of them, 13.4% (BCR: 2.5-28.6%) had LDL-cholesterol<70mg/dl, non-HDL-cholesterol<100mg/dl, and apolipoprotein B<80mg/dl. Among 832 high-risk patients, 38.7% BCR: 27.5-55.3%) were on lipid-lowering medication. Of them, 20.5% (BCR: 5.5-57.6%) had LDL-cholesterol<100mg/dl, non-HDL-cholesterol<130mg/dl, and apolipoprotein B<90mg/dl. About 96% of highest-risk patients and 94% of high-risk patients were given at least one lifestyle advice (weight reduction, healthy diet, physical activity, no-smoking), but only 1.3% of the former and 4.9% of the latter reached all three lipid goals. CONCLUSION: There is a substantial gap between clinical guidelines and medical practice since only one in 5-7 patients met all treatment targets. Although most patients received lifestyle advice, the effectiveness of counseling was very low. Large between-country differences in outcomes suggest considerable room for improvement.
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López-García, Esther
(author)
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Dallongeville, Jean
(author)
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Guallar, Eliseo
(author)
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Halcox, Julian P
(author)
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Borghi, Claudio
(author)
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Massó-González, Elvira L
(author)
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Sazova, Ogün
(author)
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Perk, JoepLinnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV)(Swepub:lnu)jpejo
(author)
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Steg, Philippe Gabriel
(author)
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De Backer, Guy
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Rodríguez-Artalejo, Fernando
(author)
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LinnéuniversitetetInstitutionen för hälso- och vårdvetenskap (HV)
(creator_code:org_t)
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In:International Journal of Cardiology: Elsevier BV166:1, s. 210-2140167-52731874-1754
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Banegas, José R
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Guallar, Eliseo
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