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  • Borghi, ClaudioUniversity of Bologna, Italy (author)

The association between blood pressure and lipid levels in Europe : European study on cardiovascular risk prevention and management in usual daily practice

  • Article/chapterEnglish2016

Publisher, publication year, extent ...

  • 2016
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:lnu-58082
  • https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-58082URI
  • https://doi.org/10.1097/HJH.0000000000001078DOI

Supplementary language notes

  • Language:English
  • Summary in:English

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  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Objectives:Several studies have suggested a positive association between serum lipid levels and blood pressure (BP). This study investigated this association in a large population from 12 European countries.Methods:Data were taken from the European Study on Cardiovascular Risk Prevention and Management in Usual Daily Practice (ClinicalTrials.gov identifier: NCT00882336). Associations between BP and lipid levels in patients free from cardiovascular disease and with at least one major cardiovascular disease risk factor (N=7641) were assessed using linear regression analyses.Results:Overall, 72.8 and 64.8% of patients had hypertension and dyslipidaemia, respectively; 47.0% had both conditions. Regression coefficients (95% confidence interval) for the associations of LDL cholesterol, non-HDL cholesterol, total cholesterol and apolipoprotein B levels with SBP, adjusted for age, sex and BMI, were 0.93mmHg/mmol per l (0.54-1.31), 1.07mmHg/mmol per l (0.73-1.40), 1.02mmHg/mmol per l (0.69-1.35) and 4.94mmHg/g per l (3.43-6.46), respectively. The corresponding values (95% confidence interval) for the associations with DBP were 0.96mmHg/mmol per l (0.73-1.19), 0.95mmHg/mmol per l (0.75-1.15), 0.87mmHg/mmol per l (0.67-1.07) and 4.33mmHg/g per l (3.42-5.23), respectively. Most of these associations remained significant whether patients were treated with statins or not.Conclusion:Small but statistically significant associations between lipid levels and BP were observed in a large, multinational European population. Further research is warranted to assess the causality of this association and its implications on the management of patients with both hypertension and dyslipidaemia.

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Added entries (persons, corporate bodies, meetings, titles ...)

  • Rodriguez-Artalejo, FernandoUniv Autonoma Madrid IdiPaz, Spain ; Inst Salud Carlos III, Spain (author)
  • De Backer, GuyUniv Ghent, Belgium (author)
  • Dallongeville, JeanUniv Lille Nord France, France (author)
  • Medina, JesúsAstraZeneca Farmaceut Spain, Spain (author)
  • Guallar, EliseoJohns Hopkins Bloomberg Sch Publ Hlth, USA ; Johns Hopkins Bloomberg Sch Publ Hlth, USA (author)
  • Perk, JoepLinnéuniversitetet,Institutionen för hälso- och vårdvetenskap (HV)(Swepub:lnu)jpejo (author)
  • Banegas, José R.Univ Autonoma Madrid IdiPaz, Spain ; Inst Salud Carlos III, Spain (author)
  • Tubach, FlorenceHop Bichat Claude Bernard, France ; ECEVE, France ; Univ Paris Diderot, France (author)
  • Roy, CarineHop Bichat Claude Bernard, France ; ECEVE, France ; Hop Bichat Claude Bernard, France (author)
  • Halcox, Julian P.Swansea Univ, UK (author)
  • University of Bologna, ItalyUniv Autonoma Madrid IdiPaz, Spain ; Inst Salud Carlos III, Spain (creator_code:org_t)

Related titles

  • In:Journal of Hypertension34:11, s. 2155-21630263-63521473-5598

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