Anti-saccades in early stages of multiple sclerosis

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Sökning: id:"swepub:oai:DiVA.org:lnu-62167" > Anti-saccades in ea...

1 av 1
Föregående post
Nästa post
Till träfflistan

Macedo, António FilipeUniversty of Minho, Portugal (författare)

Anti-saccades in early stages of multiple sclerosis

Artikel/kapitelEngelska2015

Förlag, utgivningsår, omfång ...

2015
printrdacarrier

Nummerbeteckningar

LIBRIS-ID:oai:DiVA.org:lnu-62167
https://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-62167URI

Kompletterande språkuppgifter

Språk:engelska
Sammanfattning på:engelska

Ingår i deldatabas

SwePubSwePub

Klassifikation

Ämneskategori:ref swepub-contenttype
Ämneskategori:art swepub-publicationtype

Anmärkningar

Purpose: Eye movements disability is common finding in multiple sclerosis (MS) but the exact stage at which changes are visible is not clear. The aim of study was to assess if anti-saccade (AS) planning and execution are altered at early stages of the disease.Methods: A total of 48 participants with MS selected by a neurologist (JJC) at Hospital de Braga and 52 controls participated in this study. Inclusion criteria: relapsing-remitting course, EDSS≤3, 1 month or more without MS crisis, and normal or corrected visual acuity. Exclusion criteria (MS and Control): cognitive impairment, traumatic brain injury or stroke. The mean age in the MS group was 37y and 33y in the control group. Eye movements were monitored using a binocular infrared eyetracker running at 250Hz(RED250, SMI Gmb Germany), precision <0.4deg, stimuli were presented in a 22 monitor (Dell P2210). Code for running the experiment and data analysis was written using the Matlab (Mathworks Inc). Participants were seated in a room dim light at 74cm from the monitor and head movements were minimized by a headband. The task was to fixate, after a variable period between steady fixation and the stimulus of 1250ms or 1600ms, participants looked as quickly as possible for the opposite direction where the target (a 30x30mm cross) was presented (anti-saccade movement). Each subject performed 40 trails.Results: The main results were the proportion of the directional errors (wherein the participant voluntarily looked for the wrong side), and latencies for: i) anti-saccades, ii) pro-saccades (movement in the same direction of the stimulus) and iii) correction (reaction time that the participant takes from the error fixation until to start the movement). The mean number of errors was 28%(SD=19) in MS group and 16%(SD=11) in the control group, mean difference 12%, t(74)=3.83, p<.001. Anti-saccades latency was 330msec (SD=61) in the MS group and 294ms(SD=59) in the control group, mean difference 36ms, F(1,98)=10.99, p<.05. The mean of the correction latency value was 178ms(SD=111) in the MS group and 129ms(SD=107) in the control group with a mean difference of 49ms, F(1,98)=6, p<.05. No statistically significant differences were found in accuracy and pro-saccade latency between groups.Conclusions: This study shows that anti-saccades latency and errors are increased at early stages of multiple sclerosis. Anti-saccades might be a sensitive tool to assess functional status in people with this condition.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Neurologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Neurology hsv//eng
SAMHÄLLSVETENSKAP Psykologi hsv//swe
SOCIAL SCIENCES Psychology hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Oftalmologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Ophthalmology hsv//eng
Optometry
Optometri

Biuppslag (personer, institutioner, konferenser, titlar ...)

Borges Ferreira, MarisaTEM-All with the Mutiple Sclerosis, Portugal ; Universty of Minho, Portugal (författare)
Parreira, Marta GamitoTEM-All with the Mutiple Sclerosis, Portugal (författare)
Sousa, InêsUniversty of Minho, Portugal (författare)
Figueiredo, JoséPrivate Hospital of Braga, Portugal (författare)
Cerqueira, João JoséUniversity of Minho, Portugal ; Hospital de Braga, Portugal (författare)
Silva Pereira, PauloUniversity of Minho, Portugal (författare)
Universty of Minho, PortugalTEM-All with the Mutiple Sclerosis, Portugal ; Universty of Minho, Portugal (creator_code:org_t)

Sammanhörande titlar

Ingår i:Investigative Ophthalmology and Visual Science56:70146-04041552-5783

Internetlänk

Hitta via bibliotek

Investigative Ophthalmology and Visual Science (Sök värdpublikationen i LIBRIS)

Till lärosätets databas

1 av 1
Föregående post
Nästa post
Till träfflistan

Hitta mer i SwePub

Av författaren/redakt...: Macedo, António ...; Borges Ferreira, ...; Parreira, Marta ...; Sousa, Inês; Figueiredo, José; Cerqueira, João ...; visa fler...; Silva Pereira, P ...; visa färre...

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Neurologi

SAMHÄLLSVETENSKAP: SAMHÄLLSVETENSKA ...; och Psykologi

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Oftalmologi

Artiklar i publikationen: Investigative Op ...

Av lärosätet: Linnéuniversitetet

Sök utanför SwePub

Sök vidare i:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se