Sökning: WFRF:(Wiklander Jesper G.) >
A synthetic polymer...
A synthetic polymer with avidin-like binding properties
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- Wiklander, Jesper G. (författare)
- Linnéuniversitetet,Institutionen för naturvetenskap, NV,BBCL
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- Karlsson, Björn C. G. (författare)
- Linnéuniversitetet,Institutionen för naturvetenskap, NV,BB
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- Aastrup, Teodor (författare)
- Attana AB, Stockholm
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visa fler...
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- Nicholls, Ian A. (författare)
- Linnéuniversitetet,Institutionen för naturvetenskap, NV,BBCL
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visa färre...
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(creator_code:org_t)
- 2010
- 2010
- Engelska.
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- A series of streptavidin mimicking molecularly imprinted polymers has been developed and evaluated for their biotin binding characteristics. A combination of molecular dynamics and NMR spectroscopy was used to examine potential polymer systems, in particular with the functional monomers methacrylic acid and 2-acrylamidopyridine. Synthesis of co-polymers of ethylene dimethacrylate and one or both of these functional monomers was performed. A combination of radioligand binding studies and surface area analyses (BET, SEM) demonstrated the presence of selectivity in polymers prepared using methacrylic acid as functional monomer. This correlated well with the molecular dynamics studies, showing the power of this methodology as a prognostic tool for predicting the behaviour of molecularly imprinted polymers.
Ämnesord
- NATURVETENSKAP -- Kemi -- Organisk kemi (hsv//swe)
- NATURAL SCIENCES -- Chemical Sciences -- Organic Chemistry (hsv//eng)
Nyckelord
- Organic chemistry
- Organisk kemi
- Organic Chemistry
- Organisk kemi
Publikations- och innehållstyp
- ref (ämneskategori)
- kon (ämneskategori)