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Adherence to risk m...
Adherence to risk management guidelines for drugs which cause vitamin D deficiency – big data from the Swedish health system
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- Nordqvist, Ola (författare)
- Linnéuniversitetet,Institutionen för medicin och optometri (MEO),Pharmaceutical Department, Region Kalmar County, Sweden; Linnaeus Univ, Sweden,Ctr Data Intens Sci & Applicat, DISA;DISA-IDP
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- Lönnbom Svensson, Ulrika (författare)
- Linnéuniversitetet,Institutionen för kemi och biomedicin (KOB),Linnaeus Univ, Sweden
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- Brudin, Lars, 1946- (författare)
- Linköpings universitet,Avdelningen för kardiovaskulär medicin,Medicinska fakulteten,Cty Hosp Kalmar, Sweden
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- Wanby, Pär (författare)
- Linnéuniversitetet,Institutionen för medicin och optometri (MEO),County Hospital Kalmar, Sweden,Linnaeus Univ, Sweden; Cty Hosp Kalmar, Sweden
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- Carlsson, Martin (författare)
- Linnéuniversitetet,Institutionen för medicin och optometri (MEO),County Hospital Kalmar, Sweden,Linnaeus Univ, Sweden; Cty Hosp Kalmar, Sweden
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(creator_code:org_t)
- Dove Medical Press Ltd, 2019
- 2019
- Engelska.
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Ingår i: Drug, Healthcare and Patient Safety. - : Dove Medical Press Ltd. - 1179-1365. ; 11, s. 19-28
- Relaterad länk:
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https://doi.org/10.2...
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https://liu.diva-por... (primary) (Raw object)
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https://urn.kb.se/re...
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https://doi.org/10.2...
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Abstract
Ämnesord
Stäng
- Purpose: Several medications are known to cause vitamin D deficiency. The aim of this study is to describe vitamin D testing and supplementation in patients using these “risk medications”, thereby assessing adherence to medical guidelines.Patients and methods: A database with electronic health records for the population in a Swedish County (≈240,000 inhabitants) was screened for patients prescribed the pre-defined “risk medications” during a 2-year period (2014–2015). In total, 12,194 patients were prescribed “risk medications” pertaining to one of the three included pharmaceutical groups. Vitamin D testing and concomitant vitamin D supplementation, including differences between the included pharmaceutical groups, was explored by matching personal identification numbers.Results: Corticosteroids were prescribed to 10,003 of the patients, antiepileptic drugs to 1,101, and drugs mainly reducing vitamin D uptake to 864. Two hundred twenty-six patients were prescribed >1 “risk medication”. Seven hundred eighty-seven patients (6.5%) had been tested during the 2-year period. There were no differences regarding testing frequency between groups. Concomitant supplements were prescribed to 3,911 patients (32.1%). It was more common to be prescribed supplements when treated with corticosteroids. Vitamin D supplementation was more common among tested patients in all three groups. Women were tested and supplemented to a higher extent. The mean vitamin D level was 69 nmol/L. Vitamin D deficiency was found in 24.1% of tested patients, while 41.3% had optimal levels. It was less common to be deficient and more common to have optimal levels among patients prescribed corticosteroids.Conclusion: Adherence to medical guidelines comprising testing and supplementation of patients prescribed drugs causing vitamin D deficiency needs improvement in Sweden.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Medicinska och farmaceutiska grundvetenskaper -- Farmaceutiska vetenskaper (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Basic Medicine -- Pharmaceutical Sciences (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
Nyckelord
- Pharmacology
- Farmakologi
- drug-induced vitamin D deficiency; medication risk management; big data; electronic health records; vitamin D; precision medicine
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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