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Generation of direc...
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Matter, Lukas,1995Department of Microtechnology and Nanoscience, Chalmers University of Technology, SE 41296, Gothenburg, Sweden; Department of Microsystems Engineering, University of Freiburg, Georges-Köhler-Allee 201, GER 79110, Freiburg, Germany; Brainlinks-Braintools Center, University of Freiburg, Georges-Köhler-Allee 201, GER 79110, Freiburg, Germany; Freiburg Institute for Advanced Studies (FRIAS), University of Freiburg, Albertstraße 19, GER 79104, Freiburg, Germany,Chalmers tekniska högskola,Chalmers University of Technology,Albert-Ludwigs-Universität Freiburg,University of Freiburg
(författare)
Generation of direct current electrical fields as regenerative therapy for spinal cord injury: A review
- Artikel/kapitelEngelska2023
Förlag, utgivningsår, omfång ...
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American Institute of Physics Inc.2023
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electronicrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:ltu-102432
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https://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-102432URI
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https://doi.org/10.1063/5.0152669DOI
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https://research.chalmers.se/publication/537770URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:for swepub-publicationtype
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Validerad;2023;Nivå 2;2023-12-12 (hanlid);Funder: Health Research Council of New Zealand (HRC/Catwalk Partnership 19/895); Neurological Foundation (1952 FF); German Research Foundation (EXC 1086); European Union's Horizon 2020 Research and Innovation program (759655);Full text license: CC BY
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Electrical stimulation (ES) shows promise as a therapy to promote recovery and regeneration after spinal cord injury. ES therapy establishes beneficial electric fields (EFs) and has been investigated in numerous studies, which date back nearly a century. In this review, we discuss the various engineering approaches available to generate regenerative EFs through direct current electrical stimulation and very low frequency electrical stimulation. We highlight the electrode-tissue interface, which is important for the appropriate choice of electrode material and stimulator circuitry. We discuss how to best estimate and control the generated field, which is an important measure for comparability of studies. Finally, we assess the methods used in these studies to measure functional recovery after the injury and treatment. This work reviews studies in the field of ES therapy with the goal of supporting decisions regarding best stimulation strategy and recovery assessment for future work.
Ämnesord och genrebeteckningar
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Harland, BruceSchool of Pharmacy, The University of Auckland, NZ 1023 Auckland, New Zealand,University of Auckland
(författare)
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Raos, BradSchool of Pharmacy, The University of Auckland, NZ 1023 Auckland, New Zealand,University of Auckland
(författare)
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Svirskis, DarrenSchool of Pharmacy, The University of Auckland, NZ 1023 Auckland, New Zealand,University of Auckland
(författare)
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Asplund, MariaLuleå tekniska universitet,Omvårdnad och medicinsk teknik,Department of Microtechnology and Nanoscience, Chalmers University of Technology, SE 41296, Gothenburg, Sweden; Department of Microsystems Engineering, University of Freiburg, Georges-Köhler-Allee 201, GER 79110, Freiburg, Germany; Brainlinks-Braintools Center, University of Freiburg, Georges-Köhler-Allee 201, GER 79110, Freiburg, Germany; Freiburg Institute for Advanced Studies (FRIAS), University of Freiburg, Albertstraße 19, GER 79104, Freiburg, Germany,Albert-Ludwigs-Universität Freiburg,University of Freiburg,Chalmers tekniska högskola,Chalmers University of Technology,Luleå tekniska universitet (LTU),Luleå University of Technology (LTU)(Swepub:cth)mariaasp
(författare)
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Department of Microtechnology and Nanoscience, Chalmers University of Technology, SE 41296, Gothenburg, Sweden; Department of Microsystems Engineering, University of Freiburg, Georges-Köhler-Allee 201, GER 79110, Freiburg, Germany; Brainlinks-Braintools Center, University of Freiburg, Georges-Köhler-Allee 201, GER 79110, Freiburg, Germany; Freiburg Institute for Advanced Studies (FRIAS), University of Freiburg, Albertstraße 19, GER 79104, Freiburg, GermanyChalmers tekniska högskola
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:APL Bioengineering: American Institute of Physics Inc.7:32473-2877
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