Genetic and Epigenetic Susceptibility of Peri-Implantitis

Asa'ad, Farah,1983Gothenburg University,Göteborgs universitet,Institutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap,Institutionen för odontologi,Institute of Clinical Sciences, Department of Biomaterials,Institute of Odontology (author)

Peri-implantitis is a destructive disease of implant-supporting tissues induced by bacterial biofilm, which provokes an inflammatory host response, influenced by environmental, genetic, and epigenetic factors. Genetics is the science that deals with genes, heredity, and the variations that occur in our genes and DNA, while epigenetics refers to alterations in the gene expression that are not encoded in the DNA sequence, which result in the remodeling of the chromatin and activation or inactivation of a gene. There are three major epigenetic mechanisms: DNA methylation, histone modifications, and microRNAs. The relationship between genetics, epigenetics, and peri-implantitis has been the subject of interest in the recent years; therefore, we aim in this chapter to present the state of the art on the role of genetic and epigenetic mechanisms in peri-implantitis.

Garaicoa-Pazmiño, Carlos (author)
Larsson, Lena,1969Gothenburg University,Göteborgs universitet,Institutionen för odontologi, sektion 2,Institute of Odontology, Section 2(Swepub:gu)xlleni (author)
Göteborgs universitetInstitutionen för kliniska vetenskaper, Avdelningen för biomaterialvetenskap (creator_code:org_t)

In:Unfolding Peri-implantitis: Diagnosis, PreventionSpain : Quintessence9788489873896

By the author/editor: Asa'ad, Farah, 1 ...; Garaicoa-Pazmiño ...; Larsson, Lena, 1 ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Dentistry

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Medical Biotechn ...; and Biomaterials Sci ...

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