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Multifunctional Ginger Nanofiber Hydrogels with Tunable Absorption : The Potential for Advanced Wound Dressing Applications

Squinca, Paula (författare)
Luleå tekniska universitet,Materialvetenskap,Embrapa Instrumentation, Rua XV de Novembro 1452, 13561-206 São Carlos, SP, Brazil; Graduate Program of Chemical Engineering, Federal University of São Carlos, Rod. Washington Luís-km 235, 13565-905 São Carlos, SP, Brazil,Division of Materials Science, Department of Engineering Sciences and Mathematics, Luleå University of Technology, Luleå, Sweden; Embrapa Instrumentation, São Carlos, SP, Brazil; Graduate Program of Chemical Engineering, Federal University of São Carlos, São Carlos, SP, Brazil,Lulea Univ Technol, Sweden; Embrapa Instrumentat, Brazil; Univ Fed Sao Carlos, Brazil
Berglund, Linn (författare)
Luleå tekniska universitet,Materialvetenskap,Division of Materials Science, Department of Engineering Sciences and Mathematics, Luleå University of Technology, Luleå, Sweden,Lulea Univ Technol, Sweden
Hanna, Kristina (författare)
Linköpings universitet,Institutionen för biomedicinska och kliniska vetenskaper,Medicinska fakulteten,Region Östergötland, Katastrofmedicinskt centrum
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Rakar, Jonathan (författare)
Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Katastrofmedicinskt centrum
Junker, Johan (författare)
Linköpings universitet,Avdelningen för kirurgi, ortopedi och onkologi,Medicinska fakulteten,Region Östergötland, Katastrofmedicinskt centrum
Khalaf, Hazem, 1981- (författare)
Örebro universitet,Institutionen för medicinska vetenskaper,Cardiovascular Research Centre, School of Medical Sciences, Örebro University, SE-703 62 Örebro, Sweden,Orebro Univ, Sweden
Farinas, Cristiane S. (författare)
Embrapa Instrumentation, Rua XV de Novembro 1452, 13561-206 São Carlos, SP, Brazil; Graduate Program of Chemical Engineering, Federal University of São Carlos, Rod. Washington Luís-km 235, 13565-905 São Carlos, SP, Brazil,Embrapa Instrumentat, Brazil; Univ Fed Sao Carlos, Brazil
Oksman, Kristiina, 1959- (författare)
Luleå tekniska universitet,Materialvetenskap,Mechanical & Industrial Engineering, University of Toronto, 5 King’s College Road, Toronto, Ontario M5S 3G8, Canada,Division of Materials Science, Department of Engineering Sciences and Mathematics, Luleå University of Technology, Luleå, Sweden; Mechanical & Industrial Engineering, University of Toronto, Toronto, Ontario, Canada,Lulea Univ Technol, Sweden; Univ Toronto, Canada
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 (creator_code:org_t)
2021-07-13
2021
Engelska.
Ingår i: Biomacromolecules. - : MDPI. - 1525-7797 .- 1526-4602. ; 22:8, s. 3202-3215
Relaterad länk:
https://doi.org/10.1...
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https://pubs.acs.org...
https://liu.diva-por... (primary) (Raw object)
https://urn.kb.se/re...
https://doi.org/10.1...
https://urn.kb.se/re...
https://urn.kb.se/re...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • In this study, ginger residue from juice production was evaluated as a raw material resource for preparation of nanofiber hydrogels with multifunctional properties for advanced wound dressing applications. Alkali treatment was applied to adjust the chemical composition of ginger fibers followed by TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl radical)-mediated oxidation prior to nanofiber isolation. The effect of alkali treatment on hydrogel properties assembled through vacuum filtration without addition of any chemical cross-linker was evaluated. An outstanding absorption ability of 6200% combined with excellent mechanical properties, tensile strength of 2.1 ± 0.2 MPa, elastic modulus of 15.3 ± 0.3 MPa, and elongation at break of 25.1%, was achieved without alkali treatment. Furthermore, the absorption capacity was tunable by applying alkali treatment at different concentrations and by adjusting the hydrogel grammage. Cytocompatibility evaluation of the hydrogels showed no significant effect on human fibroblast proliferation in vitro. Ginger essential oil was used to functionalize the hydrogels by providing antimicrobial activity, furthering their potential as a multifunctional wound dressing. 

Ämnesord

TEKNIK OCH TEKNOLOGIER  -- Industriell bioteknik -- Biomaterial (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Industrial Biotechnology -- Bio Materials (hsv//eng)
TEKNIK OCH TEKNOLOGIER  -- Kemiteknik -- Polymerteknologi (hsv//swe)
ENGINEERING AND TECHNOLOGY  -- Chemical Engineering -- Polymer Technologies (hsv//eng)

Nyckelord

Trä och bionanokompositer
Wood and Bionanocomposites

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ref (ämneskategori)
art (ämneskategori)

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