Sökning: WFRF:(Karlsson Sundbaum Johanna) >
Multiple manifestat...
Multiple manifestations of uncontrolled asthma increase the risk of severe COVID-19
-
- Selberg, Stina (författare)
- Umeå universitet,Avdelningen för medicin,Department of Public Health and Clinical Medicine, Division of Medicine/the OLIN-unit, Umeå University, Umeå, Sweden
-
- Karlsson Sundbaum, Johanna (författare)
- Luleå tekniska universitet,Hälsa, medicin och rehabilitering,Department of Health, Education and Technology, Luleå University of Technology, Luleå, Sweden
-
- Konradsen, Jon R. (författare)
- Karolinska Institutet
-
visa fler...
-
- Backman, Helena (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Department of Public Health and Clinical Medicine, Section of Sustainable Health/The OLIN-unit, Umeå University, Umeå, Sweden
-
- Hedman, Linnea, 1979- (författare)
- Umeå universitet,Avdelningen för hållbar hälsa,Department of Public Health and Clinical Medicine, Section of Sustainable Health/The OLIN-unit, Umeå University, Umeå, Sweden
-
- Lindberg, Anne (författare)
- Umeå universitet,Avdelningen för medicin,Department of Public Health and Clinical Medicine, Division of Medicine/the OLIN-unit, Umeå University, Umeå, Sweden
-
- Stridsman, Caroline (författare)
- Umeå universitet,Avdelningen för medicin,Department of Public Health and Clinical Medicine, Division of Medicine/the OLIN-unit, Umeå University, Umeå, Sweden
-
visa färre...
-
(creator_code:org_t)
- Elsevier, 2023
- 2023
- Engelska.
-
Ingår i: Respiratory Medicine. - : Elsevier. - 0954-6111 .- 1532-3064. ; 216
- Relaterad länk:
-
https://doi.org/10.1...
-
visa fler...
-
https://ltu.diva-por... (primary) (Raw object)
-
https://umu.diva-por... (primary) (Raw object)
-
https://urn.kb.se/re...
-
https://doi.org/10.1...
-
https://urn.kb.se/re...
-
http://kipublication...
-
visa färre...
Abstract
Ämnesord
Stäng
- ObjectiveAsthma control is of importance when assessing the risk of severe outcomes of COVID-19. The aim of this study was to explore associations of clinical characteristics and the effect of multiple manifestations of uncontrolled asthma with severe COVID-19.MethodsIn 2014–2020, adult patients with uncontrolled asthma, defined as Asthma Control Test (ACT) ≤19 were identified in the Swedish National Airway Register (SNAR) (n = 24533). The SNAR database, including clinical data, was linked with national registers to identify patients with severe COVID-19 (n = 221). The effect of multiple manifestations of uncontrolled asthma was based on: 1) ACT ≤15, 2) frequent exacerbations and 3) previous asthma inpatient/secondary care and evaluated stepwise. Poisson regression analyses were conducted with severe COVID-19 as the dependent variable.ResultsIn this cohort with uncontrolled asthma, obesity was the strongest independent risk factor for severe COVID-19 in both sexes, but even greater in men. Multiple manifestations of uncontrolled asthma were more common among those with severe COVID-19 vs. without: one, 45.7 vs. 42.3%, two, 18.1 vs. 9.1% and three, 5.0 vs. 2.1%. The risk ratio (RR) of severe COVID-19 increased with an increasing number of manifestations of uncontrolled asthma: one, RR 1.49 (95% CI 1.09–2.02), two, RR 2.42 (95% CI 1.64–3.57) and three, RR 2.96 (95% CI 1.57–5.60), when adjusted for sex, age, and BMI.ConclusionsIt is important to consider the effect of multiple manifestations of uncontrolled asthma and obesity when assessing patients with COVID-19, as this increases the risk of severe outcomes substantially.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Lungmedicin och allergi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Respiratory Medicine and Allergy (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
Nyckelord
- Asthma
- COVID-19
- Asthma control test (ACT)
- Uncontrolled asthma
- Exacerbation
- Obesity
- Quality register
- Register studies
- Medicinsk vetenskap
- Medical Science
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas