A randomized controlled trial on immediate surgery versus root planing in patients with advanced periodontal disease : a cost-effectiveness analysis

• AimTo compare immediate surgery to scaling and root planing (SRP) in the treatment of advanced periodontal disease focusing on the prevalence of residual sites and cost-effectiveness (1); to evaluate the adjunctive effects of azithromycin in a second treatment phase (2). Materials and MethodsThirty-nine patients (18 males, 21 females; mean age: 54.6) received oral hygiene instructions and were randomly allocated to surgery (n=19) or SRP (n=20). Patients with residual pockets (6mm) at 6months received re-debridement of these sites and systemic azithromycin. Treatment groups were followed up to 12months and evaluated in terms of clinical response parameters and cost-effectiveness. Chair-time was used to assess the financial impact of treatment. ResultsBoth treatment arms were equally effective in terms of clinical outcome demonstrating less than 1% residual pockets at 12months. Surgery imposed an extra 746 Euro on the patient up to 6months when compared to SRP. At 12months, 46 Euro of this amount could be offset as a result of a reduced need for supportive care. Only 6 patients in the surgery group needed systemic antibiotics, whereas 14 patients in the SRP needed such additional treatment. ConclusionsAlthough 700 Euro could be saved on average by performing SRP instead of surgery, the latter significantly reduced the need for supportive care and systemic antibiotics.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Odontologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Dentistry (hsv//eng)

Nyckelord

azithromycin

cost effectiveness

periodontitis

randomized controlled trial

scaling and root planing

surgery

Publikations- och innehållstyp

ref (ämneskategori)

art (ämneskategori)