The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral halitosis-A randomized clinical trial.

Erovic Ademovski, SeidaSchool for Health and Society, Kristianstad University, Kristianstad, Sweden,Högskolan Kristianstad, SWE,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL) (author)

LIBRIS-ID:oai:DiVA.org:mau-17811
https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-17811URI
https://doi.org/10.1111/jcpe.12779DOI
https://urn.kb.se/resolve?urn=urn:nbn:se:bth-15336URI
oai:researchportal.hkr.se/admin:publications/217aea24-2c02-41f8-a8ba-d89d36deb644URI

AIM: To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral halitosis.MATERIALS AND METHODS: Forty-six adults with intra-oral halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral halitosis was evaluated at baseline, 3 and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2 S) and methyl mercaptan (MM) concentrations in exhaled air.RESULTS: A Zn/CHX mouth rinse provided significantly better control of intra-oral halitosis than a placebo mouth rinse. At 3 and 6 months, individuals rinsing with the Zn/CHX rinse presented with reductions of the OLS, T-VSC (p < .01, respectively), H2 S (p < .001), and MM (p < .01) in subjects' exhaled air. At 6 months, 68.2% of individuals using the Zn/CHX rinse experienced a 1 or 2 category improvement in OLS compared with 19.1% of placebo-treated subjects. 91% of subjects in the Zn/CHX group were categorized as being effectively treated for intra-oral halitosis (i.e. H2 S < 112 ppb), compared to 43% in the placebo group.CONCLUSION: Zn/CHX mouth rinse provides effective long-term efficacy against intra-oral halitosis, assessed both objectively and subjectively. With regular rinsing, the effect was sustained for 6 months.

Mårtensson, CarinaSchool for Health and Society, Kristianstad University, Kristianstad, Sweden,Högskolan Kristianstad, SWE,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)(Swepub:hkr)e398b6fb-0a6b-4943-95fd-196e274e7fbe (author)
Persson, Gösta RutgerSchool for Health and Society, Kristianstad University, Kristianstad, Sweden; Department of Periodontics, School of Dentistry, University of Washington, Seattle, WA, USA,Högskolan Kristianstad, SWE,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL) (author)
Renvert, StefanBlekinge Tekniska Högskola,Institutionen för hälsa,Oral Health - Public Health - Quality of Life (OHAL),Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)(Swepub:hkr)10896a6c-95b9-43c1-9cbc-8ca94700e206 (author)
School for Health and Society, Kristianstad University, Kristianstad, SwedenHögskolan Kristianstad, SWE (creator_code:org_t)

In:Journal of Clinical Periodontology: John Wiley & Sons44:10, s. 1010-10190303-69791600-051X

By the author/editor: Erovic Ademovski ...; Mårtensson, Cari ...; Persson, Gösta R ...; Renvert, Stefan

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Dentistry

By the university: Malmö University; Blekinge Institute of Technology; Kristianstad University College

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