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Salivary microbial ...
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Lira-Junior, RonaldoKarolinska Institutet
(author)
Salivary microbial profiles in relation to age, periodontal, and systemic diseases
- Article/chapterEnglish2018
Publisher, publication year, extent ...
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2018-03-14
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Public Library of Science,2018
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printrdacarrier
Numbers
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LIBRIS-ID:oai:DiVA.org:mau-6657
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https://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-6657URI
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https://doi.org/10.1371/journal.pone.0189374DOI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:137950121URI
Supplementary language notes
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Language:English
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Summary in:English
Part of subdatabase
Classification
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Background Analysis of saliva is emerging as a promising tool to diagnose and monitor diseases which makes determination of the salivary microbial profile in different scenarios essential. Objective To evaluate the effects of age, periodontal disease, sex, smoking, and medical conditions on the salivary microbial profile. Design A randomly selected sample of 441 individuals was enrolled (51% women; mean age 48.5 +/- 16.8). Participants answered a health questionnaire and underwent an oral examination. Stimulated saliva was collected and the counts of 41 bacteria were determined by checkerboard DNA-DNA hybridization. Results Elderly participants (>64 years old) presented a significant increase in 24 out of 41 bacterial species compared to adults (<= 64 years old). Eubacterium nodatum, Porphyromonas gingivalis, and Tannerella forsythia were significantly higher in participants with generalized bone loss compared to without. Males and non-smokers had higher bacteria counts in saliva. Individuals having mental disorders or muscle and joint diseases showed significantly altered microbial profiles whereas small or no differences were found for subjects with high blood pressure, heart disease, previous heart surgery, bowel disease, tumors, or diabetes. Conclusion Age, periodontal status, sex, smoking, and certain medical conditions namely, mental disorders and muscle and joint diseases, might affect the microbial profile in saliva.
Subject headings and genre
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Multidisciplinary Sciences
Added entries (persons, corporate bodies, meetings, titles ...)
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Åkerman, SigvardMalmö universitet,Odontologiska fakulteten (OD)(Swepub:mau)odsiak
(author)
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Klinge, BjörnMalmö universitet,Odontologiska fakulteten (OD),Karolinska Institutet, Department of Dental Medicine, Division of Oral Diseases, Stockholm, Sweden(Swepub:mau)odbjkl
(author)
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Boström, Elisabeth A.Karolinska Institutet
(author)
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Gustafsson, AndersKarolinska Institutet
(author)
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Karolinska InstitutetOdontologiska fakulteten (OD)
(creator_code:org_t)
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In:PLOS ONE: Public Library of Science13:31932-6203
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