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Hypercoagulability ...
Hypercoagulability in acute bleeding peptic ulcer disease assessed by thrombin-antithrombin III concentrations.
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- Henriksson, Anders E. (författare)
- Department of Surgery, Sundsvall County Hospital, Sundsvall, Sweden
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- Nilsson, T K (författare)
- Department of Surgery, Sundsvall County Hospital, Sundsvall, Sweden
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- Svensson, J O (författare)
- Department of Surgery, Sundsvall County Hospital, Sundsvall, Sweden
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(creator_code:org_t)
- 1993
- 1993
- Engelska.
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Ingår i: European Journal of Surgery. - 1102-4151 .- 1741-9271. ; 159:3, s. 167-9
- Relaterad länk:
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https://urn.kb.se/re...
Abstract
Ämnesord
Stäng
- OBJECTIVE: To find out whether patients with acute bleeding peptic ulcers have hypercoagulable blood.DESIGN: Prospective open study.SETTING: District hospital in Sweden.SUBJECTS: 54 consecutive patients with duodenal ulcer (n = 25) and gastric ulcer (n = 29) admitted with haematemesis or melaena, or both.INTERVENTIONS: Diagnosis verified on admission by endoscopy, and healing was examined at follow up. Consumption of non-steroidal anti-inflammatory drugs, and smoking habits, were recorded.MAIN OUTCOME MEASURES: Coagulation of the blood monitored by concentrations of plasma thrombin-antithrombin III (TAT) complex in samples obtained on admission for the acute bleeding episode and at follow up 1-2 months later.RESULTS: The plasma TAT complex concentrations were raised during the acute bleeding episode (p < 0.001) compared with an age matched reference group. The TAT complex concentrations measured at follow up had returned to the reference range in all patients, whether or not their ulcers had healed.CONCLUSION: The results indicate that patients with acute haemorrhage from peptic ulcers have hypercoagulable blood during the acute episode.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine (hsv//eng)
Nyckelord
- Gastrointestinal haemorrhage
- Hypercoagulation
- Thrombin-antithrombin III complex
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
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