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Infant locomotive development and its association with adult blood pressure.

Pillas, Demetris (författare)
Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, W2 1PG, United Kingdom
Kaakinen, Marika (författare)
Institute of Health Sciences, University of Oulu, Oulu, Finland
Tzoulaki, Ioanna (författare)
Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, W2 1PG, United Kingdom
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Netuveli, Gopalakrishnan (författare)
Department of Primary care and Social Medicine, Faculty of Medicine, Imperial College London, London, United Kingdom
Rodriguez, Alina (författare)
Mittuniversitetet,Avdelningen för psykologi,Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, W2 1PG, United Kingdom
Fung, Erik (författare)
Section of Cardiology, Heart and Vascular Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH, United States
Tammelin, Tuija H (författare)
LIKES - Research Center for Sport and Health Sciences, Jyväskylä, Finland
Blane, David (författare)
Department of Primary care and Social Medicine, Faculty of Medicine, Imperial College London, London, United Kingdom
Millwood, Iona Y (författare)
Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), University of Oxford, Oxford, United Kingdom
Hardy, Rebecca (författare)
MRC Unit for Lifelong Health and Ageing, Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, United Kingdom
Sovio, Ulla (författare)
Department of Obstetrics and Gynaecology, University of Cambridge, Cambridge, United Kingdom
Pouta, Anneli (författare)
Department of Children, Young People, and Families, National Institute of Health and Welfare, Oulu, Finland
Hopstock, Laila Arnesdatter (författare)
Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway
Hartikainen, Anna-Liisa (författare)
Department of Clinical Sciences/ Obstetrics and Gynecology, University of Oulu, Oulu, Finland
Laitinen, Jaana (författare)
Finnish Institute of Occupational Health, Oulu, Finland
Vaara, Sarianna (författare)
Department of Children, Young People, and Families, National Institute of Health and Welfare, Oulu, Finland
Khan, Anokhi Ali (författare)
Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, W2 1PG, United Kingdom
Chong, Raymond (författare)
Department of Physical Therapy, Georgia Regents University, Augusta, GA, United States
Elliott, Paul (författare)
Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, W2 1PG, United Kingdom
Jarvelin, Marjo-Riitta (författare)
Department of Epidemiology and Biostatistics, Imperial College London, Norfolk Place, London, W2 1PG, United Kingdom
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 (creator_code:org_t)
2014-05-08
2014
Engelska.
Ingår i: European Journal of Pediatrics. - : Springer Science and Business Media LLC. - 0340-6199 .- 1432-1076. ; 173:10, s. 1309-17
Relaterad länk:
https://miun.diva-po... (primary) (Raw object)
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http://miun.diva-por...
https://urn.kb.se/re...
https://doi.org/10.1...
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  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • UNLABELLED: Evidence from animal models suggests that locomotion and blood pressure share common neurophysiological regulatory systems. As a result of this common regulation, we hypothesized that the development of locomotion in human infants would be associated with blood pressure levels in adulthood. The study sample comprised 4,347 individuals with measures of locomotive and non-locomotive neuromotor development in infancy and adult blood pressure levels within a longitudinal birth cohort study, the Northern Finland Birth Cohort 1966. Later development in all three stages of locomotive development during infancy was associated with higher systolic and diastolic blood pressure levels at age 31. For age of walking without support, 0.34 (95 % CI 0.07 to 0.60)-mm Hg higher SBP and 0.38 (95 % CI 0.15 to 0.62)-mm Hg higher DBP were estimated for each month of later achievement (P = 0.012 for SBP; P = 0.001 for DBP). No association was identified for non-locomotive neuromotor development.CONCLUSION: These results highlight the positive sequelae of advanced locomotive development during infancy, suggesting that the common regulatory systems between locomotion and blood pressure may influence the development of raised blood pressure over time.

Nyckelord

Neurodevelopment
Infancy
Child development
Blood pressure
Epidemiology
Cohort studies

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