Emerging manufacturing bioengineering technologies 2: Scaffold designing experiment using titanium scaffolds

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: id:"swepub:oai:DiVA.org:miun-23532" > Emerging manufactur...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

Bujtar, PeterSouthern General Hospital, Glasgow (author)

Emerging manufacturing bioengineering technologies 2: Scaffold designing experiment using titanium scaffolds

Article/chapterEnglish2014

Publisher, publication year, extent ...

Elsevier BV,2014
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:miun-23532
https://urn.kb.se/resolve?urn=urn:nbn:se:miun:diva-23532URI
https://doi.org/10.1016/j.bjoms.2014.07.059DOI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Substantial volume defects of the head and neck oftenrequire customized solutions to improve quality of life likefree flap transfers.Titanium and its alloys are versatile materialsproviding the feature of osteointegration. The conditionswhich facilitate the deposition of lamellar bone are underextensive research. Our project aimed to determine whethertitanium can function as a scaffold - unlike simple plates - toenhance bone regeneration for load bearing structures. Thereaction of stem cells to scaffolds with varying stiffness willbe presented.Additive manufacturing were used to produce a variety ofscaffolds to optimize titanium structures. Electric beam melting(EBM) manufacturing allowed us to optimize the elasticmodulus (Young) of the titanium to match with cadaveric bone from a previous project. Multidirectional mechanicaltests were performed on the various designs of titanium cellstructures (n=80). The predictability and quality of manufacturingwas assessed statistically and also with scanningelectron microscope (SEM).The results demonstrated structures matching the mechanicalproperties of bone and even anisotropy as our resultssuggest 3GPa elasticity. This allows the possibility to buildregenerating bone with predictable properties. In addition,predictable patterning - unlike etching and sandblasting - ofmicroscopic (nano) features found to be significant and nonhomogenous simple repetitive patterns provide better cellularresponse.The benefit that tissue engineering techniques offer isdecreased morbidity, relative independence from donor site,with a highly specific and customized shape. Titanium basedreconstruction constructs seems to offer an alternative futurefor bony reconstruction.

Subject headings and genre

TEKNIK OCH TEKNOLOGIER Materialteknik Metallurgi och metalliska material hsv//swe
ENGINEERING AND TECHNOLOGY Materials Engineering Metallurgy and Metallic Materials hsv//eng
TEKNIK OCH TEKNOLOGIER Medicinteknik Annan medicinteknik hsv//swe
ENGINEERING AND TECHNOLOGY Medical Engineering Other Medical Engineering hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Odontologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Dentistry hsv//eng
Additive manufacturing
implants
scaffolds
Ti64

Added entries (persons, corporate bodies, meetings, titles ...)

Simonovics, JanosSouthern General Hospital, Glasgow (author)
Koptyug, Andrey,1956-Mittuniversitetet,Avdelningen för ekoteknik och hållbart byggande,SportsTech(Swepub:miun)andkop (author)
George, SandorSouthern General Hospital, Glasgow (author)
Varadi, KarolySouthern General Hospital, Glasgow (author)
Southern General Hospital, GlasgowAvdelningen för ekoteknik och hållbart byggande (creator_code:org_t)

Related titles

In:British Journal of Oral & Maxillofacial Surgery: Elsevier BV52:8, s. e60-e610266-43561532-1940

Internet link

Find in a library

British Journal of Oral & Maxillofacial Surgery (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Bujtar, Peter; Simonovics, Jano ...; Koptyug, Andrey, ...; George, Sandor; Varadi, Karoly

About the subject

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Materials Engine ...; and Metallurgy and M ...

ENGINEERING AND TECHNOLOGY: ENGINEERING AND ...; and Medical Engineer ...; and Other Medical En ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Dentistry

Articles in the publication: British Journal ...

By the university: Mid Sweden University

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se