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Effectiveness of an...
Effectiveness of an add-on treatment with the homeopathic medication SilAtro-5-90 in recurrent tonsillitis : An international, pragmatic, randomized, controlled clinical trial
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- Palm, Jürgen (author)
- ENT Practice, Röthenbach an der Pegnitz, Germany
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- Kishchuk, Vasyl V. (author)
- ENT Department, Vinnytsia Regional Clinical Hospital Named after M.I. Pirogov, Vinnytsia, Ukraine
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- Ulied, Àngels (author)
- Pediatric Department, CAP Centelles, Centelles, Spain
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- Fernández, Joaquin P. (author)
- ENT and Homeopathy Department, Clinical Tres Torres Clinical Pilar, Barcelona, Spain
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- De Jaegere, Sabine (author)
- Deutsche Homöopathie-Union, DHU-Arzneimittel GmbH & Co. KG, Karlsruhe, Germany
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- Jong, Miek C., 1968- (author)
- Mittuniversitetet,Avdelningen för omvårdnad,Department Nutrition & Health, Louis Bolk Institute, Driebergen, The Netherlands; National Information and Knowledge Center on Integrative Medicine (NIKIM), Amsterdam, The Netherlands
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- Keller, Thomas (author)
- ACOMED statistik, Leipzig, Germany
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- Kosakovskyi, Anatolii (author)
- ENT Department, National Children Specialized Hospital OHMATDYT, Kyiv, Ukraine
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- Kompaniiets, Kira (author)
- Medical Center LLC Inter, Lugansk, Ukraine
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- Mityuryayeva-Korniiko, Inga (author)
- Policlinic Department, Children Clinical Hospital No 6 of Pecherskyi District of Kyiv, Kyiv, Ukraine
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- Pukhlik, Sergiy M. (author)
- Department of Otorhinolaryngology, Centre of Reconstructive and Renewal Medicine, University Clinic, Odessa National Medical University, Odessa, Ukraine
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- Tretiakevych, Zoia (author)
- Out-Patient Department, Lugansk Regional Children's Hospital, Lugansk, Ukraine
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- Weber, Stephan (author)
- ACOMED statistik, Leipzig, Germany
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- Wienhold, Karin (author)
- HNOprax, ENT Practice, Wuppertal, Germany
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- Klement, Petra (author)
- Deutsche Homöopathie-Union, DHU-Arzneimittel GmbH & Co. KG, Karlsruhe, Germany
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ENT Practice, Röthenbach an der Pegnitz, Germany ENT Department, Vinnytsia Regional Clinical Hospital Named after MI. Pirogov, Vinnytsia, Ukraine (creator_code:org_t)
- Elsevier BV, 2017
- 2017
- English.
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In: Complementary Therapies in Clinical Practice. - : Elsevier BV. - 1744-3881 .- 1873-6947. ; 28, s. 181-191
- Related links:
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https://miun.diva-po... (primary) (Raw object)
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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Abstract
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- Objective To investigate the effectiveness and safety of the homeopathic product SilAtro-5-90 in recurrent tonsillitis. Methods In this international, pragmatic, controlled clinical trial, 256 patients (6–60 years) with moderate recurrent tonsillitis were randomized to receive either SilAtro-5-90 in addition to standard symptomatic treatment, or to receive standard treatment only. The primary outcome was the mean time period between consecutive acute throat infections (ATI) within 1 year (analyzed via repeated events analysis). Results During the evaluation year, the risk of getting an ATI was significantly lower (hazard ratio: 0.45, proportional means model, p = 0.0002, ITT) with SilAtro-5-90 compared to control. Tonsillitis-specific symptoms were significantly reduced (p < 0.0001, ITT) and the need of antibiotics to treat acute throat infections (p = 0.0008; ITT) decreased. 3 non-serious adverse drug reactions were reported for SilAtro-5-90. Conclusions An integrative treatment approach where SilAtro-5-90 is given alongside mainstream symptomatic treatment may bring therapeutic benefit to patients suffering from recurrent tonsillitis. Trial registration: ISRCTN registry: Registration number ISRCTN19016626, registered 23 January 2013.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Omvårdnad (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nursing (hsv//eng)
Keyword
- Acute throat infection
- Homeopathy
- Randomized controlled trial
- Recurrent tonsillitis
- SilAtro-5-90
- Tonsilotren
Publication and Content Type
- ref (subject category)
- art (subject category)
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Palm, Jürgen
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Kishchuk, Vasyl ...
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Ulied, Àngels
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Fernández, Joaqu ...
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De Jaegere, Sabi ...
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Jong, Miek C., 1 ...
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Keller, Thomas
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Kosakovskyi, Ana ...
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Kompaniiets, Kir ...
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Mityuryayeva-Kor ...
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Pukhlik, Sergiy ...
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Tretiakevych, Zo ...
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Weber, Stephan
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Wienhold, Karin
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Klement, Petra
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MEDICAL AND HEAL ...
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Complementary Th ...
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Mid Sweden University