Study of DNA-Coated Nanoparticles as Possible Programmable Self-Assembly Building-Blocks

• Nanoparticles coated with single stranded DNA have been shown to efficiently hybridize to targets of complementary DNA. This property might be used to implement programmable (or algorithmic) self-assembly to build nanoparticle structures. However, we argue that a DNA coated nanoparticle by itself cannot be used as a programmable self-assembly building block since it does not have directed bonds. A general scheme for assembling and purifying nanoparticle eight-mers with eight geometrically well-directed bonds is presented together with some preliminary experimental work.  

Nyckelord

PSA

programmable self-assembly

nanotechnology

Nanoparticles

Nanostructure

Gold particles

DNA coated nanoparticles

nanoteknik

NATURAL SCIENCES

NATURVETENSKAP

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