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COVID-19 Vaccinatio...
COVID-19 Vaccination In Autoimmune Diseases (COVAD) Study : Vaccine Safety In Idiopathic Inflammatory Myopathies
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- Gil-Vila, Albert (författare)
- Systemic Autoimmune Diseases Unit, Vall d'Hebron General Hospital, Medicine Dept, Universitat Autónoma de Barcelona, Barcelona, Spain
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- Naveen, R. (författare)
- Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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- Selva-O'Callaghan, Albert (författare)
- Systemic Autoimmune Diseases Unit, Vall d'Hebron General Hospital, Medicine Dept, Universitat Autónoma de Barcelona, Barcelona, Spain
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- Sen, Parikshit (författare)
- Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi, India
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- Nune, Arvind (författare)
- Southport and Ormskirk Hospital NHS Trust, Southport, UK
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- Gaur, Prithvi Sanjeevkumar (författare)
- Smt. Kashibai Navale Medical and General Hospital, Pune, India
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- Gonzalez, Raquel Arànega (författare)
- Internal Medicine Department, Hospital Clinic, Consorci Sanitari del Maresme, Mataró, Barcelona, Spain
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- Lilleker, James B. (författare)
- Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Neurology, Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust, Salford, UK
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- Joshi, Mrudula (författare)
- Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India
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- Agarwal, Vishwesh (författare)
- Mahatma Gandhi Mission Medical College, Navi Mumbai, Maharashtra, India
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- Kardes, Sinan (författare)
- Department of Medical Ecology and Hydroclimatology, Istanbul Faculty of Medicine, Istanbul University, Capa-Fatih, Istanbul, Turkey
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- Kim, Minchul (författare)
- Center for Outcomes Research, Department of Internal Medicine, University of Illinois College of Medicine Peoria, Illinois, US
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- Day, Jessica (författare)
- Department of Rheumatology, Royal Melbourne Hospital, Parkville, VIC, Australia; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia
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- Makol, Ashima (författare)
- Division of Rheumatology, Mayo Clinic, Rochester, MN, USA
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- Milchert, Marcin (författare)
- Department of Internal Medicine, Rheumatology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland
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- Gheita, Tamer (författare)
- Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt
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- Salim, Babur (författare)
- Rheumatology Department, Fauji Foundation Hospital, Rawalpindi, Pakistan
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- Velikova, Tsvetelina (författare)
- Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, Sofia, Bulgaria
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- Gracia-Ramos, Abraham Edgar (författare)
- Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P, Mexico City, Mexico
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- Parodis, Ioannis, 1981- (författare)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden; Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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- Nikiphorou, Elena (författare)
- Centre for Rheumatic Diseases, King's College London, London, UK; Rheumatology Department, King's College Hospital, London, UK
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- Tan, Ai Lyn (författare)
- NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK
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- Chatterjee, Tulika (författare)
- Center for Outcomes Research, Department of Internal Medicine, University of Illinois College of Medicine Peoria, Illinois, USA
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- Cavagna, Lorenzo (författare)
- Department of Rheumatology, Fondazione I.R.C.C.S. Policlinico San Matteo, Pavia, Italy; Rheumatology Unit, Dipartimento di Medicine Interna e Terapia Medica, Università degli studi di Pavia, Pavia, Lombardy, Italy
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- Saavedra, Miguel A (författare)
- Departamento de Reumatología Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, IMSS, Mexico City, Mexico
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- Shinjo, Samuel Katsuyuki (författare)
- Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
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- Ziade, Nelly (författare)
- Rheumatology Department, Saint-Joseph University, Beirut, Lebanon; Rheumatology Department, Hotel-Dieu de France Hospital, Beirut, Lebanon
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- Knitza, Johannes (författare)
- Medizinische Klinik 3 - Rheumatologie und Immunologie, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland
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- Kuwana, Masataka (författare)
- Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan
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- Distler, Oliver (författare)
- Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
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- Chinoy, Hector (författare)
- Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK; Department of Rheumatology, Salford Royal Hospital Northern Care Alliance NHS Foundation Trust, Salford, UK
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- Agarwal, Vikas (författare)
- Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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- Aggarwal, Rohit (författare)
- Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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- Gupta, Latika (författare)
- Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India; Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Dept of Rheumatology, Royal Wolverhampton Hospital NHS Trust, Wolverhampton, United Kingdom; City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom
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COVAD Study Group, - (bidragsgivare)
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(creator_code:org_t)
- 2022-08-08
- 2022
- Engelska.
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Ingår i: Muscle and Nerve. - : John Wiley & Sons. - 0148-639X .- 1097-4598. ; 66:4, s. 426-437
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- INTRODUCTION/AIMS: We studied COVID-19 vaccination-related adverse events (ADEs) 7-days post-vaccination in patients with idiopathic inflammatory myopathies (IIMs) and other systemic autoimmune and inflammatory disorders (SAIDs).METHODS: 7-day vaccine ADEs were collected in an international patient self-reported e-survey. Descriptive statistics and multivariable regression were performed.RESULTS: 10,900 respondents [1227 IIMs; 4640 SAIDs; 5033 healthy controls (HCs), median age 42 (IQR 30-55) years, 74% female, 45% Caucasian, 69% completely vaccinated] were analysed. 76.3% IIMs patients reported minor and 4.6% major ADEs. Patients with active IIMs reported more frequent major [OR 2.7 (1.04-7.3)] and minor [OR 1.5 (1.1-2.2)] ADEs than inactive IIMs. Rashes were more frequent in IIMs [OR-2.3(1.2-4.2)] than HCs. ADEs were not impacted by steroid dose, although hydroxychloroquine and intravenous/subcutaneous immunoglobulins were associated with a higher risk of minor ADEs [OR 1.9 (1.1-3.3), OR 2.2 (1.1-4.3)]. Overall, ADEs were less frequent in inclusion body myositis (IBM) and BNT162b2 (Pfizer) vaccine recipients DISCUSSION: 7-day post-vaccination ADEs were comparable in patients with IIMs, SAIDs, and HCs, except for a higher risk of rashes in IIMs. Patients with DM, active disease may be at higher risk, and IBM patients at lower risk of specific ADEs. Overall, the benefit of preventing severe COVID-19 through vaccination likely outweighs the risk of vaccine-related ADEs Our results may inform future guidelines regarding COVID-19 vaccination in patients with SAIDs, and specifically in IIMs. Studies to evaluate long-term outcomes and disease flares are needed to shed more light on developing future COVID-19 vaccination guidelines.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)
Nyckelord
- COVID-19
- dermatomyositis
- myositis
- rheumatology
- vaccination
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Till lärosätets databas
- Av författaren/redakt...
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Gil-Vila, Albert
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Naveen, R.
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Selva-O'Callagha ...
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Sen, Parikshit
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Nune, Arvind
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Gaur, Prithvi Sa ...
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visa fler...
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Gonzalez, Raquel ...
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Lilleker, James ...
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Joshi, Mrudula
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Agarwal, Vishwes ...
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Kardes, Sinan
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Kim, Minchul
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Day, Jessica
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Makol, Ashima
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Milchert, Marcin
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Gheita, Tamer
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Salim, Babur
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Velikova, Tsvete ...
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Gracia-Ramos, Ab ...
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Parodis, Ioannis ...
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Nikiphorou, Elen ...
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Tan, Ai Lyn
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Chatterjee, Tuli ...
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Cavagna, Lorenzo
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Saavedra, Miguel ...
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Shinjo, Samuel K ...
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Ziade, Nelly
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Knitza, Johannes
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Kuwana, Masataka
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Distler, Oliver
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Chinoy, Hector
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Agarwal, Vikas
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Aggarwal, Rohit
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Gupta, Latika
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COVAD Study Grou ...
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MEDICIN OCH HÄLS ...
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och Klinisk medicin
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- Artiklar i publikationen
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Muscle and Nerve
- Av lärosätet
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Örebro universitet
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Karolinska Institutet