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High prevalence of ...
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Ahmad, IrmaDepartment of Infectious Diseases, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Department of Radiation Oncology, Stanford University, Stanford, CA, United States,Örebro Univ, Fac Med & Hlth, Dept Infect Dis, Örebro, Sweden.
(författare)
High prevalence of persistent symptoms and reduced health-related quality of life 6 months after COVID-19
- Artikel/kapitelEngelska2023
Förlag, utgivningsår, omfång ...
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2023-02-02
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Frontiers Media S.A.2023
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:oru-104509
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-104509URI
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https://doi.org/10.3389/fpubh.2023.1104267DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-205360URI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-498893URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
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BACKGROUND: The long-term sequelae after COVID-19 constitute a challenge to public health and increased knowledge is needed. We investigated the prevalence of self-reported persistent symptoms and reduced health-related quality of life (HRQoL) in relation to functional exercise capacity, 6 months after infection, and explored risk factors for COVID-19 sequalae.METHODS: This was a prospective, multicenter, cohort study including 434 patients. At 6 months, physical exercise capacity was assessed by a 1-minute sit-to-stand test (1MSTST) and persistent symptoms were reported and HRQoL was evaluated through the EuroQol 5-level 5-dimension (EQ-5D-5L) questionnaire. Patients with both persistent symptoms and reduced HRQoL were classified into a new definition of post-acute COVID syndrome, PACS+. Risk factors for developing persistent symptoms, reduced HRQoL and PACS+ were identified by multivariable Poisson regression.RESULTS: Persistent symptoms were experienced by 79% of hospitalized, and 59% of non-hospitalized patients at 6 months. Hospitalized patients had a higher prevalence of self-assessed reduced overall health (28 vs. 12%) and PACS+ (31 vs. 11%). PACS+ was associated with reduced exercise capacity but not with abnormal pulse/desaturation during 1MSTST. Hospitalization was the most important independent risk factor for developing persistent symptoms, reduced overall health and PACS+.CONCLUSION: Persistent symptoms and reduced HRQoL are common among COVID-19 survivors, but abnormal pulse and peripheral saturation during exercise could not distinguish patients with PACS+. Patients with severe infection requiring hospitalization were more likely to develop PACS+, hence these patients should be prioritized for clinical follow-up after COVID-19.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Edin, Alicia,1985-Umeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.(Swepub:umu)alalid03
(författare)
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Granvik, ChristofferUmeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.(Swepub:umu)chgr0038
(författare)
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Kumm Persson, LowaUmeå universitet,Institutionen för kirurgisk och perioperativ vetenskap,Umeå Univ, Dept Surg & Perioperat Sci, Umeå, Sweden.
(författare)
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Tevell, Staffan,1975-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Infectious Diseases, Karlstad Hospital, Karlstad, Sweden; Centre for Clinical Research and Education, Region Värmland, Karlstad, Sweden; School of Medical Sciences, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Karlstad Hosp, Dept Infect Dis, Karlstad, Sweden.;Ctr Clin Res & Educ, Karlstad, Sweden.;Örebro Univ, Fac Med & Hlth, Sch Med Sci, Örebro, Sweden.(Swepub:oru)stl
(författare)
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Månsson, EmeliUppsala universitet,Centrum för klinisk forskning, Västerås
(författare)
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Magnuson, AndersCenter for Clinical Epidemiology and Biostatistics, Faculty of Medicine and Health, School of Medical Sciences, Örebro University, Örebro, Sweden,Örebro Univ, Fac Med & Hlth, Ctr Clin Epidemiol & Biostat, Sch Med Sci, Örebro, Sweden.
(författare)
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Marklund, IngelaUmeå universitet,Institutionen för samhällsmedicin och rehabilitering,Centre for Clinical Research and Education, Region Värmland, Karlstad, Sweden,Ctr Clin Res & Educ, Karlstad, Sweden.;Umeå Univ, Dept Community Med & Rehabil, Umeå, Sweden.(Swepub:umu)inamad99
(författare)
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Persson, Ida-LisaUmeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.(Swepub:umu)idpe0053
(författare)
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Kauppi, AnnaUmeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.(Swepub:umu)anakai97
(författare)
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Ahlm, Clas,1956-Umeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.(Swepub:umu)clah0001
(författare)
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Forsell, Mattias N. E.Umeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.(Swepub:umu)mafo0173
(författare)
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Sundh, Josefin,1972-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Respiratory Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Örebro Univ, Fac Med & Hlth, Dept Resp Med, Örebro, Sweden.(Swepub:oru)jnsh
(författare)
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Lange, Anna,1975-Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Infectious Diseases,Department of Radiation Oncology, Stanford University, Stanford, CA, United States,Örebro Univ, Fac Med & Hlth, Dept Infect Dis, Örebro, Sweden.(Swepub:oru)aalg
(författare)
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Cajander, Sara,1980-Örebro universitet,Institutionen för medicinska vetenskaper,Department of Infectious Diseases, Faculty of Medicine and Health, Örebro University, Örebro, Sweden,Department of Radiation Oncology, Stanford University, Stanford, CA, United States,Örebro Univ, Fac Med & Hlth, Dept Infect Dis, Örebro, Sweden.(Swepub:oru)scr
(författare)
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Normark, JohanUmeå universitet,Institutionen för klinisk mikrobiologi,Umeå Univ, Dept Clin Microbiol, Umeå, Sweden.(Swepub:umu)jono0053
(författare)
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Department of Infectious Diseases, Faculty of Medicine and Health, Örebro University, Örebro, SwedenDepartment of Radiation Oncology, Stanford University, Stanford, CA, United States
(creator_code:org_t)
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Ingår i:Frontiers in Public Health: Frontiers Media S.A.112296-2565
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Ahmad, Irma
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Edin, Alicia, 19 ...
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Granvik, Christo ...
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Kumm Persson, Lo ...
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Tevell, Staffan, ...
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Månsson, Emeli
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Magnuson, Anders
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Marklund, Ingela
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Persson, Ida-Lis ...
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Kauppi, Anna
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Ahlm, Clas, 1956 ...
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Forsell, Mattias ...
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Sundh, Josefin, ...
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Lange, Anna, 197 ...
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Cajander, Sara, ...
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Normark, Johan
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