Clinical manifestations of Lyme neuroborreliosis in children: a review

Bruinsma, R. A.Lyme Center Apeldoorn, Gelre Hospital, Apeldoorn, P.O. Box 9014, 7300 DS, the Netherlands; Department of Pediatrics, Gelre Hospital, Apeldoorn, the Netherlands,Gelre Hosp, Lyme Ctr Apeldoorn, POB 9014, NL-7300 Apeldoorn, Netherlands.;Gelre Hosp, Dept Pediat, Apeldoorn, Netherlands. (författare)

Clinical manifestations of Lyme neuroborreliosis in children : a review

Lyme neuroborreliosis (LNB) is a manifestation of Lyme disease involving the central and peripheral nervous system. It is caused by the spirochete Borrelia burgdorferi, transmitted by tick bites to a human host. Clinical signs of LNB develop after the dissemination of the pathogen to the nervous system. The infection occurs in children and adults, but the clinical manifestations differ. In adults, painful meningoradicultis is the most common manifestation of LNB, while children often present with facial nerve palsy and/or subacute meningitis. Subacute headache can be the only manifestation of LNB in children, especially during the summer months in Lyme disease-endemic regions. Non-specific symptoms, such as loss of appetite, fatigue or mood changes, may also occur, especially in young children. A high level of suspicion and early recognition of the various clinical manifestations presented by children with LNB is essential to minimize delay in diagnosis and optimize management. This review provides an overview of the spectrum of clinical manifestations, and discusses diagnosis, antibiotic treatment, and clinical outcome of LNB in children.

Zomer, T. P.Lyme Center Apeldoorn, Gelre Hospital, Apeldoorn, P.O. Box 9014, 7300 DS, the Netherlands,Gelre Hosp, Lyme Ctr Apeldoorn, POB 9014, NL-7300 Apeldoorn, Netherlands. (författare)
Skogman, Barbro Hedin,1967-Uppsala universitet,Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Center for Clinical Research Dalarna, Uppsala University, Falun, Sweden; Department of Medical Sciences, Örebro University, Örebro, Sweden,Centrum för klinisk forskning Dalarna,Örebro Univ, Dept Med Sci, Örebro, Sweden.(Swepub:uu)barhe734 (författare)
van Hensbroek, M. BoeleDepartment of Pediatrics, Amsterdam Medical Center, University of Amsterdam, Amsterdam, the Netherlands,Univ Amsterdam, Amsterdam Med Ctr, Dept Pediat, Amsterdam, Netherlands. (författare)
Hovius, J. W.Amsterdam UMC Multidisciplinary Lyme borreliosis Center, Amsterdam UMC Medical Centers, location AMC, University of Amsterdam, Amsterdam, the Netherlands,Univ Amsterdam, Amsterdam UMC Multidisciplinary Lyme borreliosis C, Amsterdam UMC Med Ctr, locat AMC, Amsterdam, Netherlands. (författare)
Lyme Center Apeldoorn, Gelre Hospital, Apeldoorn, P.O. Box 9014, 7300 DS, the Netherlands; Department of Pediatrics, Gelre Hospital, Apeldoorn, the NetherlandsGelre Hosp, Lyme Ctr Apeldoorn, POB 9014, NL-7300 Apeldoorn, Netherlands.;Gelre Hosp, Dept Pediat, Apeldoorn, Netherlands. (creator_code:org_t)

Ingår i:European Journal of Pediatrics: Springer182:5, s. 1965-19760340-61991432-1076

Av författaren/redakt...: Bruinsma, R. A.; Zomer, T. P.; Skogman, Barbro ...; van Hensbroek, M ...; Hovius, J. W.

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Infektionsmedici ...

Av lärosätet: Örebro universitet; Karolinska Institutet; Uppsala universitet

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