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Type 1 diabetes, CO...
Type 1 diabetes, COVID-19 vaccines and short-term safety : Subgroup analysis from the global COVAD study
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- Chatterjee, Tulika (författare)
- Department of Internal Medicine, Center for Outcomes Research, University of Illinois College of Medicine Peoria, Peoria, Illinois, USA
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- Ravichandran, Naveen (författare)
- Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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- Nair, Narmadha (författare)
- Department of Endocrinology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK
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- Gracia-Ramos, Abraham Edgar (författare)
- Department of Internal Medicine, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, General Hospital, Mexico City, Mexico
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- Barman, Bhupen (författare)
- Department of Medicine, All India Institute of Medical Science (AIIMS), Guwahati, India
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- Sen, Parikshit (författare)
- Maulana Azad Medical College, New Delhi, Delhi, India
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- Joshi, Mrudula (författare)
- Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India
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- Saha, Sreoshy (författare)
- Mymensingh Medical College, Mymensingh, Bangladesh
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- Nune, Arvind (författare)
- Department of Rheumatology, Southport and Ormskirk Hospital NHS Trust, Southport, UK
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- Pande, Arun Kumar R. (författare)
- LEDTC Clinic, Lucknow, Uttar Pradesh, India
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- Velikova, Tsvetelina (författare)
- Medical Faculty, Sofia University St. Kliment Ohridski, Sofia, Bulgaria
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- Parodis, Ioannis, 1981- (författare)
- Örebro universitet,Institutionen för medicinska vetenskaper,Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden; Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
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- Tan, Ai Lyn (författare)
- NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK
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- Shinjo, Samuel Katsuyuki (författare)
- Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
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- Boro, Hiya (författare)
- Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India
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- Agarwal, Vikas (författare)
- Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
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- Aggarwal, Rohit (författare)
- Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
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- Gupta, Latika (författare)
- Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK; Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine, and Health, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Sandwell and West Birmingham Hospitals NHS Trust, City Hospital, Birmingham, UK
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COVAD Study Group, - (bidragsgivare)
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(creator_code:org_t)
- John Wiley & Sons, 2024
- 2024
- Engelska.
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Ingår i: Journal of Diabetes Investigation. - : John Wiley & Sons. - 2040-1116 .- 2040-1124. ; 15:1, s. 131-138
- Relaterad länk:
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https://doi.org/10.1...
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https://urn.kb.se/re...
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https://doi.org/10.1...
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http://kipublication...
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Abstract
Ämnesord
Stäng
- AIMS/INTRODUCTION: Coronavirus disease 2019 (COVID-19) vaccinations have been proven to be generally safe in healthy populations. However, the data on vaccine safety in patients with type 1 diabetes are scarce. This study aimed to evaluate the frequency and severity of short-term (<7-day) adverse vaccination events (AEs) and their risk factors among type 1 diabetes patients. MATERIALS AND METHODS: This study analyzed data from the COVID-19 vaccination in Autoimmune Diseases (COVAD) survey database (May to December 2021; 110 collaborators, 94 countries), comparing <7-day COVID-19 vaccine AE among type 1 diabetes patients and healthy controls (HCs). Descriptive statistics; propensity score matching (1:4) using the variables age, sex and ethnicity; and multivariate analyses were carried out.RESULTS: This study analyzed 5,480 completed survey responses. Of all responses, 5,408 were HCs, 72 were type 1 diabetes patients (43 females, 48.0% white European ancestry) and Pfizer was the most administered vaccine (39%). A total of 4,052 (73.9%) respondents had received two vaccine doses. Patients with type 1 diabetes had a comparable risk of injection site pain, minor and major vaccine AEs, as well as associated hospitalizations to HCs. However, type 1 diabetes patients had a higher risk of severe rashes (3% vs 0.4%, OR 8.0, 95% confidence interval 1.7-36), P = 0.007), although reassuringly, these were rare (n = 2 among type 1 diabetes patients).CONCLUSIONS: COVID-19 vaccination was safe and well tolerated in patients with type 1 diabetes with similar AE profiles compared with HCs, although severe rashes were more common in type 1 diabetes patients.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)
Nyckelord
- COVID-19
- Type 1 diabetes mellitus
- Vaccine
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- Av författaren/redakt...
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Chatterjee, Tuli ...
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Ravichandran, Na ...
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Nair, Narmadha
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Gracia-Ramos, Ab ...
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Barman, Bhupen
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Sen, Parikshit
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visa fler...
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Joshi, Mrudula
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Saha, Sreoshy
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Nune, Arvind
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Pande, Arun Kuma ...
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Velikova, Tsvete ...
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Parodis, Ioannis ...
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Tan, Ai Lyn
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Shinjo, Samuel K ...
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Boro, Hiya
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Agarwal, Vikas
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Aggarwal, Rohit
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Gupta, Latika
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COVAD Study Grou ...
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- MEDICIN OCH HÄLSOVETENSKAP
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MEDICIN OCH HÄLS ...
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Journal of Diabe ...
- Av lärosätet
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Örebro universitet
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Karolinska Institutet