Silica Exposure and Cardiovascular, Cerebrovascular, and Respiratory Morbidity in a Cohort of Male Swedish Iron Foundry Workers

Andersson, Lena,1965-Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Department of Occupational and Environmental Medicine (author)

In this study, we present quantitative exposure-response data on silica exposure in male Swedish iron foundry workers receiving inpatient care for cardiovascular, cerebrovascular, and respiratory morbidity. The study show a significantly increased COPD risk at cumulative silica exposures that correspond to TWA silica below the Swedish OEL of 0.1 mg/m3. ObjectiveWe present quantitative exposure-response data on silica exposure in male Swedish iron foundry workers for cardiovascular, cerebrovascular, and respiratory morbidity.MethodsThis research is a cohort study of 2063 male Swedish iron foundry workers. From the Swedish National Patient Registers, data on morbidity incidence were retrieved. A historical measurement database of 1667 respirable silica exposure measurements from 10 Swedish iron foundries was used to calculate the cumulative exposure dose for each worker.ResultsIncreased morbidity risk for the whole group of foundry workers was determined for ischemic heart disease, cerebrovascular disease, chronic obstructive pulmonary disease (COPD), bronchitis, and pneumonia. In addition, an increased risk for COPD at cumulative silica exposures ranging from 0.11 to 0.84 mg/m3 year is presented.ConclusionsThe study presents a significantly increased COPD risk at cumulative silica exposures below the Swedish occupational exposure limit.

Hedbrant, Alexander,Ph.D,1987-Örebro universitet,Institutionen för medicinska vetenskaper(Swepub:oru)arht (author)
Bryngelsson, Ing-LissDepartment of Occupational and Environmental Medicine, Örebro University Hospital, Örebro, Sweden (author)
Vihlborg, Per,1978-Örebro universitet,Institutionen för medicinska vetenskaper,Region Örebro län,Geriatric Clinic(Swepub:oru)prvg (author)
Särndahl, Eva,1963-Örebro universitet,Institutionen för medicinska vetenskaper(Swepub:oru)easl (author)
Westberg, Håkan,1949-Örebro universitet,Institutionen för naturvetenskap och teknik,Inflammatory Response and Infection Susceptibility Centre (iRiSC), Faculty of Medicine and Health Örebro University, Örebro, Sweden; Department of Occupational and Environmental Medicine(Swepub:oru)hwg (author)
Örebro universitetInstitutionen för medicinska vetenskaper (creator_code:org_t)

In:Journal of Occupational and Environmental Medicine: Lippincott Williams & Wilkins65:9, s. 731-7391076-27521536-5948

By the author/editor: Andersson, Lena, ...; Hedbrant, Alexan ...; Bryngelsson, Ing ...; Vihlborg, Per, 1 ...; Särndahl, Eva, 1 ...; Westberg, Håkan, ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Public Health Gl ...

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.