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Gender differences in patient experience in idiopathic inflammatory myopathies : Sub analysis from the COVAD dataset

Yoshida, Akira (författare)
Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan
Kim, Minchul (författare)
Center for Outcomes Research, Department of Internal Medicine, University of Illinois College of Medicine Peoria, USA
Kuwana, Masataka (författare)
Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan
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Ravichandran, Naveen (författare)
Department of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
Makol, Ashima (författare)
Division of Rheumatology, Mayo Clinic, Rochester, USA
Sen, Parikshit (författare)
Maulana Azad Medical College, New Delhi, India
Lilleker, James B. (författare)
Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Neurology, Manchester Centre for Clinical Neurosciences, Northern Care Alliance NHS Foundation Trust, Salford, UK
Agarwal, Vishwesh (författare)
Mahatma Gandhi Mission Medical College, Navi Mumbai, India
Kardes, Sinan (författare)
Department of Medical Ecology and Hydroclimatology, Istanbul Faculty of Medicine, Istanbul University, Capa-Fatih, Turkey
Day, Jessica (författare)
Department of Rheumatology, Royal Melbourne Hospital, Parkville, Australia; Walter and Eliza Hall Institute of Medical Research, Parkville, Australia; Department of Medical Biology, University of Melbourne, Parkville, Australia
Milchert, Marcin (författare)
Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland
Joshi, Mrudula (författare)
Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India
Gheita, Tamer (författare)
Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt
Salim, Babur (författare)
Rheumatology Department, Fauji Foundation Hospital, Rawalpindi, Pakistan
Velikova, Tsvetelina (författare)
Medical Faculty, Sofia University St. Kliment Ohridski, Sofia, Bulgaria
Gracia-Ramos, Abraham Edgar (författare)
Department of Internal Medicine, General Hospital, National Medical Center 'La Raza', Instituto Mexicano del Seguro Social, Mexico City, Mexico
Parodis, Ioannis, 1981- (författare)
Örebro universitet,Institutionen för medicinska vetenskaper,Division of Rheumatology, Department of Medicine Solna, Karolinska Institutet and Karolinska University Hospital, Sweden; Department of Rheumatology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
Nikiphorou, Elena (författare)
Centre for Rheumatic Diseases, King's College London, London, UK; Rheumatology Department, King's College Hospital, London, UK
Chatterjee, Tulika (författare)
Center for Outcomes Research, Department of Internal Medicine, University of Illinois College of Medicine Peoria, USA
Tan, Ai Lyn (författare)
NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK
Nune, Arvind (författare)
Southport and Ormskirk Hospital NHS Trust, Southport, UK
Cavagna, Lorenzo (författare)
Department of Rheumatology, Fondazione I.R.C.C.S. Policlinico San Matteo, Pavia, Italy; Rheumatology Unit, Dipartimento di Medicine Interna e Terapia Medica, Università degli studi di Pavia, Pavia, Italy
Saavedra, Miguel A. (författare)
Departamento de Reumatología Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, IMSS, Mexico City, Mexico
Shinjo, Samuel Katsuyuki (författare)
Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil
Ziade, Nelly (författare)
Rheumatology Department, Saint-Joseph University, Beirut, Lebanon; Rheumatology Department, Hotel-Dieu de France Hospital, Beirut, Lebanon
Knitza, Johannes (författare)
Medizinische Klinik 3-Rheumatologie und Immunologie, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Deutschland
Distler, Oliver (författare)
Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
Chinoy, Hector (författare)
Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester, UK; National Institute for Health Research Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, The University of Manchester, Manchester, UK; Department of Rheumatology, Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Salford, UK
Agarwal, Vikas (författare)
Division of Rheumatology, Mayo Clinic, Rochester, USA
Aggarwal, Rohit (författare)
Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh , USA
Gupta, Latika (författare)
Division of Rheumatology, Mayo Clinic, Rochester, USA; Department of Rheumatology, Royal Wolverhampton Hospitals NHS Trust, Wolverhampton, UK; City Hospital, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK; Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester, UK
COVAD Study Group, - (bidragsgivare)
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 (creator_code:org_t)
2023
2023
Engelska.
Ingår i: Modern Rheumatology. - : Taylor & Francis. - 1439-7595 .- 1439-7609.
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
Stäng  
  • OBJECTIVES: We aimed to investigate gender-based differences in idiopathic inflammatory myopathies (IIMs), with a particular focus on patient-reported outcomes, utilizing data obtained through the international COVID-19 vaccination in autoimmune disease (COVAD) e-survey.METHODS: Patient-reported outcomes including fatigue, pain, and physical function were extracted from the COVAD database and compared between genders, adjusting for demographics and IIM subgroups by multivariable analysis. Inclusion body myositis (IBM) was analysed separately because of substantial differences in outcomes.RESULTS: 1197 complete responses from patients with IIMs as of 31 August 2021 were analysed. Seventy percent were women. Women were younger (58 [48-68] vs. 69 [58-75] years old, median [IQR], p < 0.001) and more likely to suffer from autoimmune multimorbidity, defined as three or more autoimmune diseases in an individual patient (11.4% vs. 2.8%, p < 0.001). In non-IBM IIMs, fatigue visual analogue scale scores were higher in women (5 [3-7] vs. 4 [2-6], median [IQR], p = 0.004), whereas no significant gender-based differences were noted in IBM. Multivariable analysis in non-IBM IIMs revealed women, residence in high-income countries, overlap myositis, and autoimmune multimorbidity were independently associated with increased fatigue.CONCLUSIONS: Women with IIMs suffer from autoimmune multimorbidity and experience increased fatigue compared to men.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reumatologi och inflammation (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Rheumatology and Autoimmunity (hsv//eng)

Nyckelord

E-survey
fatigue
gender difference
myositis
patient-reported outcome measures

Publikations- och innehållstyp

ref (ämneskategori)
art (ämneskategori)

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