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Regression From Early GDM to Normal Glucose Tolerance and Adverse Pregnancy Outcomes in the Treatment of Booking Gestational Diabetes Mellitus Study

Simmons, David (författare)
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Immanuel, Jincy (författare)
School of Medicine, Western Sydney University, Campbelltown, New South Wales, Australia
Hague, William M. (författare)
Robinson Research Institute, The University of Adelaide, Adelaide, South Australia, Australia
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Teede, Helena (författare)
Monash University, Melbourne, Victoria, Australia
Nolan, Christopher J. (författare)
The Canberra Hospital, Canberra, Australian Capital Territory, Australia; Australian National University, Canberra, Australian Capital Territory, Australia
Peek, Michael J. (författare)
Australian National University, Canberra, Australian Capital Territory, Australia
Flack, Jeff R. (författare)
Bankstown-Lidcombe Hospital, Sydney, New South Wales, Australia
McLean, Mark (författare)
Blacktown Hospital, Sydney, New South Wales, Australia
Wong, Vincent W. (författare)
Liverpool Hospital and University of New South Wales, Liverpool, New South Wales, Australia
Hibbert, Emily J. (författare)
Nepean Clinical School, Faculty of Medicine and Health, University of Sydney, and Nepean Hospital, Sydney, New South Wales, Australia
Kautzky-Willer, Alexandra (författare)
Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria
Harreiter, Jürgen (författare)
Gender Medicine Unit, Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria; Department of Medicine, Landesklinikum Scheibbs, Scheibbs, Austria
Backman, Helena, 1965- (författare)
Örebro universitet,Institutionen för hälsovetenskaper,Department of Obstetrics and Gynecology
Gianatti, Emily (författare)
Endocrinology and Diabetes, Fiona Stanley Fremantle Hospitals Group, Murdoch, Western Australia, Australia
Sweeting, Arianne (författare)
Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia
Mohan, Viswanathan (författare)
Dr. Mohan's Diabetes Specialities Centre and Madras Diabetes Research Foundation, Chennai, India
Cheung, N. Wah (författare)
Westmead Hospital, Sydney, New South Wales, Australia
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 (creator_code:org_t)
2024
2024
Engelska.
Ingår i: Diabetes Care. - 0149-5992 .- 1935-5548.
  • Tidskriftsartikel (refereegranskat)
Abstract Ämnesord
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  • OBJECTIVE: To compare pregnancy outcomes among women with a normal oral glucose tolerance test (OGTT) before 20 weeks' gestation (early) and at 24-28 weeks' gestation (late) (no gestational diabetes mellitus, or No-GDM), those with early GDM randomized to observation with a subsequent normal OGTT (GDM-Regression), and those with GDM on both occasions (GDM-Maintained).RESEARCH DESIGN AND METHODS: Women at <20 weeks' gestation with GDM risk factors who were recruited for a randomized controlled early GDM treatment trial were included. Women with treated early GDM and late GDM (according to the World Health Organization's 2013 criteria) were excluded from this analysis. Logistic regression compared pregnancy outcomes.RESULTS: GDM-Regression (n = 121) group risk factor profiles and OGTT results generally fell between the No-GDM (n = 2,218) and GDM-Maintained (n = 254) groups, with adjusted incidences of pregnancy complications similar between the GDM-Regression and No-GDM groups.CONCLUSIONS: Women with early GDM but normal OGTT at 24-28 weeks' gestation had pregnancy outcomes that were similar to those of individuals without GDM. Identifying early GDM likely to regress would allow treatment to be avoided.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)
MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Endokrinologi och diabetes (hsv//swe)
MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Endocrinology and Diabetes (hsv//eng)

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