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Sökning: WFRF:(Tsianos Epameinondas V.) > (2014) > Initial Disease Cou...

  • Burisch, JohanMed Sect, Ctr Digest Dis, Herlev Univ Hosp, Copenhagen, Denmark (författare)

Initial Disease Course and Treatment in an Inflammatory Bowel Disease Inception Cohort in Europe : The ECCO-EpiCom Cohort

  • Artikel/kapitelEngelska2014

Förlag, utgivningsår, omfång ...

  • Lippincott Williams & Wilkins,2014
  • printrdacarrier

Nummerbeteckningar

  • LIBRIS-ID:oai:DiVA.org:oru-33695
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-33695URI
  • https://doi.org/10.1097/01.MIB.0000436277.13917.c4DOI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:128031886URI

Kompletterande språkuppgifter

  • Språk:engelska
  • Sammanfattning på:engelska

Ingår i deldatabas

Klassifikation

  • Ämneskategori:ref swepub-contenttype
  • Ämneskategori:art swepub-publicationtype

Anmärkningar

  • Funding Agencies:Danish Colitis Crohn Patients Organization     Vibeke Binder and Povl Riis' Foundation     Scientific Council at the Herlev Hospital     Sigrid Rigmor Moran Foundation     Aage and Johanne Louis-Hansens Foundation     Munkholm FoundationC.C. Klestrup and Henriette Klestrup FoundationKnud and Dagny Gad Andresens FoundationElse and Mogens Wedell-Wedellsborgs FoundationDirektor Jacob Madsen and Olga Madsens Foundation     ScanVet     Torben og Alice Frimodt Foundation     Laegernes forsikringsforening     Bengt Ihres Foundation     Nanna Svartz Foundation     Orebro University Hospital Research Foundation     Orebro County Research Foundation     Swedish Foundation for Gastrointestinal Research     Swedish Society of Medicine     Research Council of South-East Sweden     County Council of Ostergotland     Swedish Organization for the Study of Inflammatory Bowel Disease     Competitive State Research Financing of the Expert Responsibility Area of Tampere University Hospital     European Crohn's and Colitis Organization
  • Background:The EpiCom cohort is a prospective, population-based, inception cohort of inflammatory bowel disease (IBD) patients from 31 European centers covering a background population of 10.1 million. The aim of this study was to assess the 1-year outcome in the EpiCom cohort.Methods:Patients were followed-up every third month during the first 12 (3) months, and clinical data, demographics, disease activity, medical therapy, surgery, cancers, and deaths were collected and entered in a Web-based database (www.epicom-ecco.eu).Results:In total, 1367 patients were included in the 1-year follow-up. In western Europe, 65 Crohn's disease (CD) (16%), 20 ulcerative colitis (UC) (4%), and 4 IBD unclassified (4%) patients underwent surgery, and in eastern Europe, 12 CD (12%) and 2 UC (1%) patients underwent surgery. Eighty-one CD (20%), 80 UC (14%), and 13 (9%) IBD unclassified patients were hospitalized in western Europe compared with 17 CD (16%) and 12 UC (8%) patients in eastern Europe. The cumulative probability of receiving immunomodulators was 57% for CD in western (median time to treatment 2 months) and 44% (1 month) in eastern Europe, and 21% (5 months) and 5% (6 months) for biological therapy, respectively. For UC patients, the cumulative probability was 22% (4 months) and 15% (3 months) for immunomodulators and 6% (3 months) and 1% (12 months) for biological therapy, respectively in the western and eastern Europe.Discussion:In this cohort, immunological therapy was initiated within the first months of disease. Surgery and hospitalization rates did not differ between patients from eastern and western Europe, although more western European patients received biological agents and were comparable to previous population-based inception cohorts.

Ämnesord och genrebeteckningar

Biuppslag (personer, institutioner, konferenser, titlar ...)

  • Pedersen, NataliaMed Sect, Ctr Digest Dis, Herlev Univ Hosp, Copenhagen, Denmark (författare)
  • Cukovic-Cavka, SilvjaUniv Hosp Ctr Zagreb, Div Gastroenterol & Hepatol, Univ Zagreb School of Medicine, Zagreb, Croatia (författare)
  • Turk, NiksaUniv Hosp Ctr Zagreb, Div Gastroenterol & Hepatol, Univ Zagreb School of Medicine, Zagreb, Croatia (författare)
  • Kaimakliotis, IoannisNicosia Private Practice, Nicosia, Cyprus (författare)
  • Duricova, DanaIBD Ctr ISCARE, Charles Univ Prague, Prague, Czech Republic (författare)
  • Shonova, OlgaDept Gastroenterol, Hosp Ceske Budejovice, Ceske Budejovice, Czech Republic (författare)
  • Vind, IdaDept Med, Amager Hosp, Amager, Denmark (författare)
  • Avnstrom, SorenDept Med, Amager Hosp, Amager, Denmark (författare)
  • Thorsgaard, NielsDept Med, Herning Cent Hosp, Herning, Denmark (författare)
  • Krabbe, SusanneDept Med, Viborg Reg Hosp, Viborg, Denmark (författare)
  • Andersen, VibekeMedical Department, Viborg Regional Hospital, Viborg, Denmark; Medical Department, Hospital of Southern Jutland, Aabenraa, Denmark; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark (författare)
  • Jens, Frederik DahlerupDept Med Hepatol & Gastroenterol 5, Aarhus Univ Hosp, Aarhus, Denmark (författare)
  • Kjeldsen, JensDept Med Gastroenterol, Odense Univ Hosp, Odense, Denmark (författare)
  • Salupere, RiinaDiv Gastroenterol & Endocrinol, Tartu Univ Hosp, Tartu, Estonia (författare)
  • Olsen, JongeroDept Med, Natl Hosp Faroe Islands, Torshavn, Denmark (författare)
  • Nielsen, Kari RubekDept Med, Natl Hosp Faroe Islands, Torshavn, Denmark (författare)
  • Manninen, PiaDept Gastroenterol & Alimentary Tract Surg, Tampere Univ Hosp, Tampere, Finland (författare)
  • Collin, PekkaDept Gastroenterol & Alimentary Tract Surg, Tampere Univ Hosp, Tampere, Finland (författare)
  • Katsanos, Konstantinnos H.Div Internal Med 1, Univ Hosp, Ioannina, Greece ; Hepatogastroenterol Unit, Univ Hosp, Ioannina, Greece (författare)
  • Tsianos, Epameinondas V.Div Internal Med 1, Univ Hosp, Ioannina, Greece ; Hepatogastroenterol Unit, Univ Hosp, Ioannina, Greece (författare)
  • Ladefoged, KarinDept Med, Dronning Ingrids Hosp, Nuuk, Greenland (författare)
  • Lakatos, LaszloDept Med, Csolnoky F Prov Hosp, Veszprem, Hungary (författare)
  • Bailey, YvonneAdelaide & Meath Hosp, Dept Gastroenterol, Trinity Coll Dublin, Dublin, Ireland (författare)
  • O'Morain, ColmDept Gastroenterol, Adelaide & Meath Hosp, Dublin, Ireland (författare)
  • Schwartz, DoronDept Gastroenterol & Hepatol, Soroka Med Ctr, Beer Sheva, Israel; Ben Gurion Univ of the Negev, Beer Sheva, Israel (författare)
  • Odes, SelwynDept Gastroenterol & Hepatol, Soroka Med Ctr, Beer Sheva, Israel; Ben Gurion Univ of the Negev, Beer Sheva, Israel (författare)
  • Martinato, MatteoU.O. Gastroenterologia, Azienda Ospedaliera, Università di Padova, Padova, Italy (författare)
  • Lombardini, SilviaUO Medicina 38 e Gastroenterologia, Azienda Ospedaliera Arcispedale S Maria Nuova, Reggio Emilia, Italy (författare)
  • Jonaitis, LaimasInstitute for Digestive Research, Lithuanian University of Health Sciences, Kaunas, Lithuania (författare)
  • Kupcinskas, LimasDepartment of Gastroenterology, State University of Medicine and Pharmacy of the Republic of Moldova, Chisinau, Moldova (författare)
  • Turcan, SvetlanaDept Gastroenterol, State Univ Med & Pharm Republ Moldova, Kishinev, Moldova (författare)
  • Barros, LouisaDept Med, Hosp Vale de Sousa, Oporto, Portugal (författare)
  • Magro, FernandoDept Gastroenterol, Hosp Sao Joao, Oporto, Portugal ; Inst Pharmacol & Therapeut, Oporto Med Sch, Oporto, Portugal ; Inst Mol & Cell Biol, Univ Porto, Oporto, Portugal (författare)
  • Lazar, DanielaGastroenterol Clin, Univ Med 'Victor Babes', Timisoara, Romania (författare)
  • Goldis, AdrianGastroenterol Clin, Univ Med 'Victor Babes', Timisoara, Romania (författare)
  • Nikulina, InnaDepartment of Gastroenterology, Moscow Regional Research Clinical Institute, Moscow, Russian Federation (författare)
  • Belousova, ElenaDept Gastroenterol, Moscow Reg Res Clin Inst, Moscow, Russia (författare)
  • Fernandez, AlbertoDept Gastroenterol, POVISA Hosp, Vigo, Spain (författare)
  • Hernandez, VicentDept Gastroenterol, Complexo Hospitalario Univ Vigo, Vigo, Spain (författare)
  • Almer, SvenKarolinska Institutet (författare)
  • Zhulina, Yaroslava,1973-Örebro universitet,Institutionen för hälsovetenskap och medicin,Region Örebro län,Div Gastroenterol, Dept Med, Örebro University Hospital, Örebro, Sweden(Swepub:oru)yza (författare)
  • Halfvarson, Jonas,1970-Örebro universitet,Institutionen för läkarutbildning,Region Örebro län,Div Gastroenterol, Dept Med, Örebro University Hospital, Örebro, Sweden(Swepub:oru)jshn (författare)
  • Tsai, Her-HsinHull and East Yorkshire NHS Trust, Kingston-Upon-Hull, UK; Hull and York Medical School, Kingston-Upon-Hull, UK; Hull Royal Infirmary, Kingston-Upon-Hull, UK (författare)
  • Sebastian, ShajiHull and East Yorkshire NHS Trust, Kingston-Upon-Hull, UK; Hull and York Medical School, Kingston-Upon-Hull, UK; Hull Royal Infirmary, Kingston-Upon-Hull, UK (författare)
  • Lakatos, Peter LaszloDept Med 1, Semmelweis Univ, Budapest, Hungary (författare)
  • Langholz, EbbeDept Med Gastroenterol, Gentofte Univ Hosp, Copenhagen, Denmark (författare)
  • Munkholm, PiaMed Sect, Ctr Digest Dis, Herlev Univ Hosp, Copenhagen, Denmark (författare)
  • EpiCom Northern Italy Centre Based in Crema and Cremona, Padova and Reggio Emilia, Italy (Lombardini & Martinato, on behalf of ), Group author (författare)
  • Med Sect, Ctr Digest Dis, Herlev Univ Hosp, Copenhagen, DenmarkUniv Hosp Ctr Zagreb, Div Gastroenterol & Hepatol, Univ Zagreb School of Medicine, Zagreb, Croatia (creator_code:org_t)

Sammanhörande titlar

  • Ingår i:Inflammatory Bowel Diseases: Lippincott Williams & Wilkins20:1, s. 36-461078-09981536-4844

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