The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm

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Razavi, H.Ctr Dis Anal, Louisville, USA (author)

The present and future disease burden of hepatitis C virus (HCV) infection with today's treatment paradigm

Article/chapterEnglish2014

Publisher, publication year, extent ...

2014-04-08
Hoboken :Wiley-Blackwell,2014
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LIBRIS-ID:oai:DiVA.org:oru-34995
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-34995URI
https://doi.org/10.1111/jvh.12248DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:128663843URI

Supplementary language notes

Language:English
Summary in:English

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SwePubSwePub

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Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Funding Agency:Gilead Sciences
The disease burden of hepatitis C virus (HCV) is expected to increase as the infected population ages. A modelling approach was used to estimate the total number of viremic infections, diagnosed, treated and new infections in 2013. In addition, the model was used to estimate the change in the total number of HCV infections, the disease progression and mortality in 2013-2030. Finally, expert panel consensus was used to capture current treatment practices in each country. Using today's treatment paradigm, the total number of HCV infections is projected to decline or remain flat in all countries studied. However, in the same time period, the number of individuals with late-stage liver disease is projected to increase. This study concluded that the current treatment rate and efficacy are not sufficient to manage the disease burden of HCV. Thus, alternative strategies are required to keep the number of HCV individuals with advanced liver disease and liver-related deaths from increasing.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Infektionsmedicin hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Infectious Medicine hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Gastroenterologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Gastroenterology and Hepatology hsv//eng
HCV
diagnosis
treatment
hepatitis C
prevalence
epidemiology
disease burden
mortality
incidence

Added entries (persons, corporate bodies, meetings, titles ...)

Waked, I.Natl Liver Inst, Menoufia, Egypt (author)
Sarrazin, C.JW Goethe Univ Hosp, Frankfurt, Germany (author)
Myers, R. P.Liver Unit, Div Gastroenterol & Hepatol, Univ Calgary, Calgary AB, Canada (author)
Idilman, R.Dept Gastroenterol, Sch Med, Ankara Univ, Ankara, Turkey (author)
Calinas, F.Dept Gastroenterol, Ctr Hosp Lisboa Cent, Hosp Santo Antonio Capuchos, Lisbon, Portugal (author)
Vogel, W.Med Univ Innsbruck, Innsbruck, Austria (author)
Mendes Correa, M. C.Sch Med, Univ Sao Paulo, Sao Paulo, Brazil (author)
Hezode, C.Serv Hepatogastroenterol, Hop Henri Mondor, Creteil, France (author)
Lazaro, P.Adv Tech Hlth Serv Res TAISS, Madrid, Spain (author)
Akarca, U.Ege Univ, Izmir, Turkey (author)
Aleman, S.Karolinska Institutet (author)
Balik, I.Ankara Univ, Ankara, Turkey (author)
Berg, T.Univ Leipzig, Leipzig, Germany (author)
Bihl, F.Dept Gastroenterol, Osped Cantonale, Bellinzona, Switzerland (author)
Bilodeau, M.Dept Med, Liver Unit, Univ Montreal, Montreal, Canada (author)
Blasco, A. J.Adv Tech Hlth Serv Res TAISS, Madrid, Spain (author)
Brandao Mello, C. E.Dept Gastroenterol, Fed Univ State Rio de Janeiro, Rio De Janeiro, Brazil (author)
Bruggmann, P.Arud Ctr Addict Med, Zurich, Switzerland (author)
Buti, M.Biomedical Research Networking Center in Hepatic and Digestive Diseases (CIBEREHD), Hosp Valle De Hebron, Barcelona, Spain (author)
Calleja, J. L.Hosp Puerta Hierro, Madrid, Spain (author)
Cheinquer, H.Hosp Clin, Univ Fed Rio Grande do Sul, Porto Alegre RS, Brazil (author)
Christensen, P. B.Dept Infect Dis, Odense Univ Hosp, Odense, Denmark (author)
Clausen, M.Reg Hosp Hovedstaden, Copenhagen, Denmark (author)
Coelho, H. S. M.Dept Clin Med, Univ Fed Rio de Janeiro, Rio De Janeiro, Brazil (author)
Cramp, M. E.Peninsula Sch Med & Dent, Univ Plymouth, Plymouth, England (author)
Dore, G. J.Kirby Inst, Univ New S Wales, Sydney NSW, Australia (author)
Doss, W.Cairo Univ, Cairo, Egypt (author)
Duberg, Ann-Sofi,1957-Örebro universitet,Institutionen för läkarutbildning,Region Örebro län,Dept Infect Dis, Örebro University Hospital, Örebro, Sweden(Swepub:oru)adg (author)
El-Sayed, M. H.Ain Shams Univ, Cairo, Egypt (author)
Ergor, G.Dokuz Eylul Univ, Izmir, Turkey (author)
Esmat, G.Cairo Univ, Cairo, Egypt (author)
Falconer, K.Karolinska Institutet (author)
Felix, J.Exigo Consultores, Alhos Vedros, Portugal (author)
Ferraz, M. L. G.Div Gastroenterol, Univ Fed Sao Paulo, Sao Paulo, Brazil (author)
Ferreira, P. R.Div Infect Dis, Univ Fed Sao Paulo, Sao Paulo, Brazil (author)
Frankova, S.Dept Hepatogastroenterol, Inst Clin & Expt Med, Prague, Czech Republic (author)
Garcia-Samaniego, J.Biomedical Research Networking Center in Hepatic and Digestive Diseases (CIBEREHD), Hosp Carlos III, Madrid, Spain (author)
Gerstoft, J.Univ Copenhagen, Copenhagen, Denmark (author)
Giria, J. A.Direccao Geral Saude, Lisbon, Portugal (author)
Goncales, F. L., Jr.Disciplina Doencas Infecciosas, Dept Clin Med, Grp Estudo Hepatites,Fac Ciencias Med,UNICAMP, Univ Estadual Campinas, Sao Paulo, Brazil (author)
Gower, E.Ctr Dis Anal, Louisville, USA (author)
Gschwantler, M.Dept Internal Med 4, Wilhelminenspital Stadt Wien, Vienna, Austria (author)
Guimaraes Pessoa, M.Sch Med, Div Gastroenterol & Hepatol, Univ Sao Paulo, Sao Paulo, Brazil (author)
Hindman, S. J.Ctr Dis Anal, Louisville, USA (author)
Hofer, H.Div Gastroenterol & Hepatol, Dept Internal Med 3, Med Univ Vienna, Vienna, Austria (author)
Husa, P.Clin Infect Dis, Univ Hosp Brno, Masaryk Univ, Brno, Czech Republic (author)
Kåberg, M.Karolinska Institutet (author)
Kaita, K. D. E.Dept Internal Med, Sect Hepatol, Univ Manitoba, Winnipeg MB, Canada; Hlth Sci Ctr, Viral Hepatitis Invest Unit, Winnipeg MB, Canada (author)
Kautz, A.European Liver Patients Assoc, St Truiden, Belgium (author)
Kaymakoglu, S.Istanbul Univ, Istanbul, Turkey (author)
Krajden, M.British Columbia Ctr Dis Control, Univ British Columbia, Vancouver, Canada (author)
Krarup, H.Dept Med Gastroenterol, Aalborg Univ Hosp, Aalborg, Denmark; Sect Mol Diagnost, Aalborg Univ Hosp, Aalborg, Denmark (author)
Laleman, W.Univ Hosp Leuven, Katholieke Univ Leuven, Louvain, Belgium (author)
Lavanchy, D. (author)
Marinho, R. T.Dept Gastroenterol, Ctr Hosp Lisboa Norte, Hosp Santa Maria, Lisbon, Portugal (author)
Marotta, P.Div Gastroenterol, Univ Western Ontario, London ON, Canada (author)
Mauss, S.Univ Dusseldorf, Dusseldorf, Germany (author)
Moreno, C.Erasme Univ Hosp, Univ Libre Brussels, Brussels, Belgium (author)
Murphy, K.Ctr Dis Anal, Louisville, USA (author)
Negro, F.Div Gastroenterol & Hepatol, Univ Hosp, Geneva, Switzerland;Div Clin Pathol, Univ Hosp, Geneva, Switzerland (author)
Nemecek, V.Natl Inst Publ Hlth, Natl Reference Lab Hepatitis, Prague, Czech Republic (author)
Ormeci, N.Ankara Univ, Ankara, Turkey (author)
Ovrehus, A. L. H.Dept Infect Dis, Odense Univ Hosp, Odense, Denmark (author)
Parkes, J.Univ Southhampton, Southampton, England (author)
Pasini, K.Ctr Dis Anal, Louisville, USA (author)
Peltekian, K. M.Capital Dist Hlth Author, Queen Elizabeth II Hlth Sci Ctr, Dept Med,Dalhousie Univ & Hepatol Serv, Halifax NS, Canada; Capital Dist Hlth Author, Queen Elizabeth II Hlth Sci Ctr, Dept Surg, Dalhousie Univ & Hepatol Serv, Halifax NS, Canada (author)
Ramji, A.Dept Gastroenterol, Univ British Columbia, Vancouver, Canada (author)
Reis, N.Assembleia Republ, Lisbon, Portugal (author)
Roberts, S. K.Alfred Hosp, Melbourne Vic, Australia; Monash Univ, Melbourne, Australia (author)
Rosenberg, W. M.Div Med, UCL Inst Liver & Digest Hlth, University College London, London, England (author)
Roudot-Thoraval, F.Dept Sante Publ, Hop Henri Mondor, Creteil, France (author)
Ryder, S. D.Nottingham Univ Hosp NHS Trust, Nottingham, England; Biomed Res Unit, Nottingham, England (author)
Sarmento-Castro, R.Dept Infect Dis, Ctr Hosp Porto, Oporto, Portugal (author)
Semela, D.Div Gastroenterol & Hepatol, Cantonal Hosp St Gallen, St Gallen, Switzerland (author)
Sherman, M.Univ Hlth Network, Toronto Gen Hosp, Univ Toronto, Toronto, Canada (author)
Shiha, G. E.Egyptian Liver Res Inst & Hosp, Dakahliah, Egypt (author)
Sievert, W.Monash Univ, Melbourne, Australia; Monash Hlth, Melbourne Vic, Australia (author)
Sperl, J.Dept Hepatogastroenterol, Inst Clin & Expt Med, Prague, Czech Republic (author)
Starkel, P.Clin Univ St Luc, Catholic Univ Louvain, Brussels, Belgium (author)
Stauber, R. E.Div Gastroenterol & Hepatol, Dept Internal Med, Med Univ Graz, Graz, Austria (author)
Thompson, A. J.Dept Gastroenterol, St Vincents Hosp, Melbourne Vic, Australia; Univ Melbourne, Melbourne Vic, Australia (author)
Urbanek, P.Dept Internal Med, Fac Med 1, Charles Univ Prague, Prague, Czech Republic; Cent Mil Hosp, Prague, Czech Republic (author)
Van Damme, P.Univ Antwerp, Antwerp, Belgium (author)
van Thiel, I.St Truiden, Belgium; Deutsch Leberhilfe eV, European Liver Patients Assoc, Cologne, Germany (author)
Van Vlierberghe, H.Ghent Univ Hosp, Ghent, Belgium (author)
Vandijck, D.Dept Hlth Econ & Patient Safety, Belgium Hasselt Univ, Univ Ghent, Diepenbeek, Belgium (author)
Wedemeyer, H.Dept Gastroenterol Hepatol & Endocrinol, Hannover Med Sch, Hannover, Germany (author)
Weis, N.Copenhagen Univ Hosp, Hvidovre, Denmark (author)
Wiegand, J.Ankara Univ, Ankara, Turkey (author)
Yosry, A.Cairo Univ, Cairo, Egypt (author)
Zekry, A.St George Hosp Clin Sch Med, Univ New S Wales, Sydney NSW, Australia; Sch Med Sci, Univ New S Wales, Sydney NSW, Australia (author)
Cornberg, M.Dept Gastroenterol Hepatol & Endocrinol, Hannover Med Sch, Hannover, Germany (author)
Muellhaupt, B.Swiss HPB Hepatopancreatobiliary Ctr, Univ Zurich Hosp, Zurich, Switzerland; Dept Gastroenterol & Hepatol, Univ Zurich Hosp, Zurich, Switzerland (author)
Estes, C.Ctr Dis Anal, Louisville, USA (author)
Ctr Dis Anal, Louisville, USANatl Liver Inst, Menoufia, Egypt (creator_code:org_t)

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In:Journal of Viral HepatitisHoboken : Wiley-Blackwell21:Suppl. 1, s. 34-591352-05041365-2893

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By the author/editor: Razavi, H.; Waked, I.; Sarrazin, C.; Myers, R. P.; Idilman, R.; Calinas, F.; show more...; Vogel, W.; Mendes Correa, M ...; Hezode, C.; Lazaro, P.; Akarca, U.; Aleman, S.; Balik, I.; Berg, T.; Bihl, F.; Bilodeau, M.; Blasco, A. J.; Brandao Mello, C ...; Bruggmann, P.; Buti, M.; Calleja, J. L.; Cheinquer, H.; Christensen, P. ...; Clausen, M.; Coelho, H. S. M.; Cramp, M. E.; Dore, G. J.; Doss, W.; Duberg, Ann-Sofi ...; El-Sayed, M. H.; Ergor, G.; Esmat, G.; Falconer, K.; Felix, J.; Ferraz, M. L. G.; Ferreira, P. R.; Frankova, S.; Garcia-Samaniego ...; Gerstoft, J.; Giria, J. A.; Goncales, F. L., ...; Gower, E.; Gschwantler, M.; Guimaraes Pessoa ...; Hindman, S. J.; Hofer, H.; Husa, P.; Kåberg, M.; Kaita, K. D. E.; Kautz, A.; Kaymakoglu, S.; Krajden, M.; Krarup, H.; Laleman, W.; Lavanchy, D.; Marinho, R. T.; Marotta, P.; Mauss, S.; Moreno, C.; Murphy, K.; Negro, F.; Nemecek, V.; Ormeci, N.; Ovrehus, A. L. H ...; Parkes, J.; Pasini, K.; Peltekian, K. M.; Ramji, A.; Reis, N.; Roberts, S. K.; Rosenberg, W. M.; Roudot-Thoraval, ...; Ryder, S. D.; Sarmento-Castro, ...; Semela, D.; Sherman, M.; Shiha, G. E.; Sievert, W.; Sperl, J.; Starkel, P.; Stauber, R. E.; Thompson, A. J.; Urbanek, P.; Van Damme, P.; van Thiel, I.; Van Vlierberghe, ...; Vandijck, D.; Wedemeyer, H.; Weis, N.; Wiegand, J.; Yosry, A.; Zekry, A.; Cornberg, M.; Muellhaupt, B.; Estes, C.; show less...

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