Increase in physical activity is associated with lower HbA1c levels in children and adolescents with type 1 diabetes: results from a cross-sectional study based on the Swedish pediatric diabetes quality registry (SWEDIABKIDS)

Increase in physical activity is associated with lower HbA1c levels in children and adolescents with type 1 diabetes : results from a cross-sectional study based on the Swedish pediatric diabetes quality registry (SWEDIABKIDS)

Aims: To evaluate the associations between physical activity (PA) and metabolic control, measured by glycated hemoglobin (HbA1c), in a large group of children and adolescents with type 1 diabetes.Methods: Cross-sectional analysis of data from 4655 patients, comparing HbA1c values with levels of physical activity. The data for the children and adolescents were obtained from the Swedish pediatric diabetes quality registry, SWEDIABKIDS. The patients were 7-18 years of age, had type 1 diabetes and were not in remission. Patients were grouped into five groups by frequency of PA.Results: Mean HbA1c level was higher in the least physically active groups (PA0: 8.8% +/- 1.5 (72 +/- 16 mmol/mol)) than in the most physically active groups (PA4: 7.7% +/- 1.0 (60 +/- 11 mmol/mol)) (p < 0.001). An inverse dose-response association was found between PA and HbA1c (beta: -0.30, 95%CI: -0.34 to -0.26, p < 0.001). This association was found in both sexes and all age groups, apart from girls aged 7-10 years. Multiple regression analysis revealed that the relationship remained significant (beta: -0.21, 95% CI: -0.25 to -0.18, p < 0.001) when adjusted for possible confounding factors.Conclusions: Physical activity seems to influence HbA1c levels in children and adolescents with type 1 diabetes. In clinical practice these patients should be recommended daily physical activity as a part of their treatment.

Magnusson, AndersClinical Epidemiology and Biostatistic Unit, Örebro University Hospital, Örebro, Sweden (författare)
Särnblad, Stefan,1963-Örebro universitet,Institutionen för läkarutbildning,Region Örebro län,Department of Pediatrics, Örebro University Hospital, Örebro, Sweden(Swepub:oru)snsd (författare)
Åman, Jan,1948-Region Örebro län,Department of Pediatrics, Örebro University Hospital, Örebro, Sweden(Swepub:oru)jnaa (författare)
Samuelsson, UlfÖstergötlands Läns Landsting,Linköpings universitet,Avdelningen för kliniska vetenskaper,Hälsouniversitetet,Barn- och ungdomskliniken i Linköping(Swepub:liu)ulfsa43 (författare)
Linköpings universitetClinical Epidemiology and Biostatistic Unit, Örebro University Hospital, Örebro, Sweden (creator_code:org_t)

Ingår i:Diabetes Research and Clinical PracticeClare, Ireland : Elsevier105:1, s. 119-1250168-82271872-8227

Av författaren/redakt...: Beraki, Åsa; Magnusson, Ander ...; Särnblad, Stefan ...; Åman, Jan, 1948-; Samuelsson, Ulf

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Pediatrik

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Endokrinologi oc ...

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.