Changes in prevalence and incidence of HIV-1, HIV-2 and dual infections in urban areas of Bissau, Guinea-Bissau: is HIV-2 disappearing?

Changes in prevalence and incidence of HIV-1, HIV-2 and dual infections in urban areas of Bissau, Guinea-Bissau : is HIV-2 disappearing?

Objectives: To assess the changes in HIV prevalence and incidence between 1996 and 2006 in urban areas of Bissau.Design: A cross-sectional survey of 384 randomly selected houses within a community-based follow-up study of HIV-1 and HIV-2.Methods: A total of 3242 individuals aged at least 15 years were eligible for inclusion. Participants were interviewed about behavioral and socio-economic factors and had a blood sample drawn. A total of 2548 individuals were tested for antibodies to HIV-1 and HIV-2, of whom 649 had taken part in a similar survey in 1996.Results: With 0.5% HIV dual reactions included, the overall HIV-1 prevalence was 4.6% (118 out of 2548) and the HIV-2 prevalence was 4.4% (112 out of 2548). The prevalence of HIV-1 increased more for women than men especially in the 25-34-year age group. HIV-2 prevalence decreased below 45 years of age but not for individuals more than 45 years old. The incidence rate between 1996 and 2006 was 0.5 per 100 person-years for HIV-1 and 0.24 per 100 person-years for HIV-2. Compared with a previous period from 1987 to 1996, the incidence of HIV-2 is declining whereas no significant increase in the incidence of HIV-1 was observed.Conclusions: The present study shows an increasing prevalence of HIV-1 and a decreasing prevalence of HIV-2 in Guinea-Bissau. HIV is generally a bigger problem for women. Despite the general decline in prevalence, HIV-2 may continue as an infection in older people, especially women.

MEDICIN OCH HÄLSOVETENSKAP Hälsovetenskap Omvårdnad hsv//swe
MEDICAL AND HEALTH SCIENCES Health Sciences Nursing hsv//eng
SAMHÄLLSVETENSKAP Annan samhällsvetenskap Tvärvetenskapliga studier inom samhällsvetenskap hsv//swe
SOCIAL SCIENCES Other Social Sciences Social Sciences Interdisciplinary hsv//eng
MEDICIN OCH HÄLSOVETENSKAP Medicinska och farmaceutiska grundvetenskaper Mikrobiologi inom det medicinska området hsv//swe
MEDICAL AND HEALTH SCIENCES Basic Medicine Microbiology in the medical area hsv//eng
Adolescent
Adult
Aged
Aged; 80 and over
Cross-Sectional Studies
Female
Guinea-Bissau/epidemiology
HIV Infections/*epidemiology
HIV-1
HIV-2
Humans
Incidence
Male
Middle Aged
Prevalence
Urban Health
Caring sciences
Vårdvetenskap
INTERDISCIPLINARY RESEARCH AREAS
TVÄRVETENSKAPLIGA FORSKNINGSOMRÅDEN
Vårdvetenskap med inriktning arbetsterapi
Nursing Science w. Occupational Therapy Focus
prevalence
incidence
HIV-2
HIV-1
community study
Guinea-Bissau

Oliveira, Inês (author)
Andersen, Andreas (author)
Dias, Francisco (author)
Rodrigues, Amabélia (author)
Holmgren, Birgitta GLund University,Lunds universitet,Avdelningen för medicinsk mikrobiologi,Institutionen för laboratoriemedicin,Medicinska fakulteten,Division of Medical Microbiology,Department of Laboratory Medicine,Faculty of Medicine(Swepub:lu)mmb-bho (author)
Andersson, SörenÖrebro universitet,Hälsoakademin(Swepub:oru)sean (author)
Aaby, Peter (author)
Avdelningen för medicinsk mikrobiologiInstitutionen för laboratoriemedicin (creator_code:org_t)

By the author/editor: da Silva, Zacari ...; Oliveira, Inês; Andersen, Andrea ...; Dias, Francisco; Rodrigues, Amabé ...; Holmgren, Birgit ...; show more...; Andersson, Sören; Aaby, Peter; show less...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Health Sciences; and Nursing

SOCIAL SCIENCES: SOCIAL SCIENCES; and Other Social Sci ...; and Social Sciences ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Microbiology in ...

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