Sökning: WFRF:(Adamsson A) >
Electroporation the...
Electroporation therapy of skin cancer in the head and neck area.
-
- Landström, Fredrik J (författare)
- Department of Otolaryngology, Örebro University Hospital, Örebro, Sweden
-
- Nilsson, Christer O. S. (författare)
- Department of Otolaryngology, Örebro University Hospital, Örebro, Sweden
-
- Crafoord, Sven (författare)
- Örebro universitet,Institutionen för läkarutbildning,Department of Ophthalmology, Örebro University Hospital, Örebro, Sweden
-
visa fler...
-
- Reizenstein, Johan A. (författare)
- Department of Oncology, Örebro University Hospital, Örebro, Sweden
-
- Adamsson, Gun-Britt M. (författare)
- Department of Head and Neck Oncology Center, Örebro University Hospital, Örebro, Sweden
-
- Löfgren, Lennart A. (författare)
- Department of Head and Neck Oncology Center, Örebro University Hospital, Örebro, Sweden
-
visa färre...
-
(creator_code:org_t)
- Ovid Technologies (Wolters Kluwer Health), 2010
- 2010
- Engelska.
-
Ingår i: Dermatologic Surgery. - : Ovid Technologies (Wolters Kluwer Health). - 1076-0512 .- 1524-4725. ; 36:8, s. 1245-50
- Relaterad länk:
-
https://urn.kb.se/re...
-
visa fler...
-
https://doi.org/10.1...
-
visa färre...
Abstract
Ämnesord
Stäng
- BACKGROUND: Electroporation therapy is a new cancer treatment modality in which a locally applied electrical field enhances cell membrane permeability, allowing greater intracellular accumulation of a chemotherapeutic agent.OBJECTIVE: To evaluate the efficacy of electroporation therapy in treating basal cell and squamous cell carcinomas of the skin.MATERIALS AND METHODS: Six patients with skin cancer of the head and neck were treated using electroporation therapy with intratumorally injected bleomycin. Orbital growth, facial nerve proximity, or proximity to cartilage of the external meatus complicated four of these tumors. The intention was curative. The follow-up period was 24 months and included biopsies after 8 weeks.RESULTS: In four of the six patients, one treatment was enough to eradicate the tumor. In one patient, the tumor persisted even after a second treatment with electroporation therapy. A septal cartilage perforation was the only major complication. The cosmetic results were very satisfactory. One additional recurrence was recorded 6 months after the follow-up periodCONCLUSION: Electroporation therapy is a promising new cancer treatment that should be further evaluated as an alternative to surgery, especially in complicated skin cancer.
Ämnesord
- MEDICIN OCH HÄLSOVETENSKAP -- Klinisk medicin -- Cancer och onkologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Clinical Medicine -- Cancer and Oncology (hsv//eng)
Nyckelord
- Electroporation therapy
- tumor control
- basal cell carcinoma
- squamous cell carcinoma
- BCC
- SCC
- Onkologi
- Oncology
Publikations- och innehållstyp
- ref (ämneskategori)
- art (ämneskategori)
Hitta via bibliotek
Till lärosätets databas