Cancer Characteristics and Current Treatments of Patients with Renal Cell Carcinoma in Sweden

Thorstenson, AndreasUmeå universitet,Urologi och andrologi,Karolinska Institute, Stockholm, Sweden; University of Oxford, Oxford, UK,Umeå Univ, Dept Surg & Perioperat Sci, Urol & Androl, Umeå, Sweden; Karolinska Inst, Urol Sect, Dept Mol Med & Surg, Stockholm, Sweden; Univ Oxford, Nuffield Dept Surg Sci, Surg Intervent Trials Unit, Oxford, England (author)

Funding Agencies:Umeå UniversityLions Cancer Research FoundationResearch Foundation at the Urology Department of Sahlgrenska University HospitalFoundation of Anna-Lisa and Bror BjörnssonStockholm Cancer SocietyCapio S:t Görans Hospital
Methodology: Since the start in 2005 virtually all patients with newly diagnosed renal cell carcinoma (RCC) in Sweden are reported to the National Swedish Kidney Cancer Register (NSKCR). The register contains information on histopathology, nuclear grade, clinical stage, preoperative work-up, treatment, recurrence, and survival.Results: A total of 8556 patients with newly diagnosed RCC were registered in the NSKCR from 2005 to 2013 resulting in a coverage of 99% as compared to the Swedish Cancer Registry. The mean tumor size at detection decreased from 70 mm in 2005 to 64 mm in 2010. The proportion of patients who were incidentally detected increased. The proportion of patients with tumor stage T1a who underwent partial nephrectomy increased from 22% in 2005 to 56% in 2012. Similarly, the proportion of laparoscopically performed radical nephrectomies increased from 6% in 2005 to 17% in 2010. During the five years of follow-up 20% of the patients had a recurrence.Conclusion: Over the last decade there has been a trend of earlier detection and less advanced tumors at detection in patients with RCC. An increasing proportion of the patients undergo laparoscopic and nephron-sparing procedures.

Harmenberg, UlrikaDepartment of Oncology, Karolinska University Hospital, Solna, Stockholm, Sweden,Karolinska Univ Hosp, Dept Oncol, Stockholm, Sweden (author)
Lindblad, Per,1953-Örebro universitet,Institutionen för läkarutbildning,Dept Urol, Örebro University Hospital, Örebro, Sweden,Univ Örebro, Fac Med & Hlth, Dept Urol, Örebro, Sweden(Swepub:oru)pld (author)
Holmström, BennyUppsala universitet,Urologkirurgi,. (author)
Lundstam, SvenDepartment of Urology, Sahlgrenska University Hospital, Göteborg, Sweden,Sahlgrens Univ Hosp, Dept Urol, Gothenburg, Sweden (author)
Ljungberg, Börje,1949-Umeå universitet,Urologi och andrologi,Umeå Univ, Dept Surg & Perioperat Sci, Urol & Androl, Umeå, Sweden.(Swepub:umu)bolj0001 (author)
Umeå universitetUrologi och andrologi (creator_code:org_t)

In:BioMed Research International: Hindawi Publishing Corporation2314-61332314-6141

By the author/editor: Thorstenson, And ...; Harmenberg, Ulri ...; Lindblad, Per, 1 ...; Holmström, Benny; Lundstam, Sven; Ljungberg, Börje ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Basic Medicine; and Microbiology in ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Cancer and Oncol ...

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Urology and Neph ...

By the university: Örebro University; Umeå University; Karolinska Institutet; Uppsala University

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