Fasting capillary glucose as a screening test for gestational diabetes mellitus

• Objective: To evaluate fasting capillary glucose as a screening test for gestational diabetes mellitus (GDM) compared with traditional risk factors and repeated random capillary glucose measurements.Design: Cross-sectional, population-based study.Setting: Maternal Health Care Clinics in Orebro County, Sweden.Population: An unselected population of women without diabetes.Methods: Fasting capillary glucose levels were measured at gestational weeks 28-32. Random capillary glucose levels were measured four to six times during pregnancy. Traditional risk factors for GDM were registered. GDM was diagnosed using a 75-g oral glucose tolerance test.Main outcome measures: Sensitivity, specificity, likelihood ratios.Results: In 55 of 3616 women participating in the study, GDM was diagnosed before 34 weeks of gestation. For fasting capillary glucose cutoff values between 4.0 and 5.0 mmol/l, sensitivity was in the range between 87 and 47% and specificity between 51 and 96%. Using a combined screening model of traditional risk factors with fasting capillary glucose at various cutoff values increased the sensitivity only slightly compared with using fasting capillary glucose alone.Conclusion: In this Swedish, unselected, low-risk population, fasting capillary glucose measurements were found to be an acceptable and useful screening test for GDM.

Ämnesord

MEDICIN OCH HÄLSOVETENSKAP  -- Klinisk medicin -- Reproduktionsmedicin och gynekologi (hsv//swe)

MEDICAL AND HEALTH SCIENCES  -- Clinical Medicine -- Obstetrics, Gynaecology and Reproductive Medicine (hsv//eng)

Nyckelord

fasting capillary glucose; gestational diabetes mellitus; screening; sensitivity; specificity

MEDICINE

MEDICIN

Obstetrics and gynaecology

Obstetrik och gynekologi

Obstetrics and Gynaecology

Obstetrik och gynekologi

Publikations- och innehållstyp

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