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Cause of death in i...
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Duberg, Ann-SofiÖrebro universitet,Hälsoakademin
(författare)
Cause of death in individuals with chronic HBV and/or HCV infection, a nationwide community-based register study
- Artikel/kapitelEngelska2008
Förlag, utgivningsår, omfång ...
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Wiley,2008
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:oru-4744
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-4744URI
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https://doi.org/10.1111/j.1365-2893.2008.00982.xDOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-14376URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:117154715URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Part of thesis: http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-7835
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Studies on chronic viral hepatitis and mortality have often been made on selected populations or in high-endemic countries. The aim of this study was to investigate the causes of death and the mortality rates in the nationwide cohorts of people chronically infected with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) in Sweden, a low-endemic country. All notifications on chronic HBV infection and HCV infection 1990-2003 were linked to the Cause of Death Register. A total of 9517 people with chronic HBV infection, 34 235 people with HCV infection and 1601 with chronic HBV-HCV co-infection were included, and the mean observation times were 6.4, 6.3 and 7.9 years, respectively. The mortality in the cohorts was compared with age- and gender-specific mortality in the general population and standardized mortality ratios (SMR) were calculated. All-cause mortality was significantly increased, SMR 2.3 (HBV), 5.8 (HCV) and 8.5 (HBV-HCV), with a great excess liver-related mortality in all cohorts, SMR 21.7, 35.5 and 46.2, respectively. In HCV and HBV-HCV infected there was an increased mortality due to drug-related psychiatric diagnoses (SMR: 20.7 and 27.6) and external causes (SMR: 12.4 and 11.4), predominantly at younger age. To conclude, this study demonstrated an increased all-cause mortality, with a great excess mortality from liver disease, in all cohorts. In people with HCV infection the highest excess mortality in younger ages was from drug-related and external reasons.PMID: 18397223 [PubMed - indexed for MEDLINE]
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
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Törner, Anna
(författare)
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Davidsdóttir, Lóa
(författare)
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Aleman, SooKarolinska Institutet
(författare)
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Blaxhult, AndersKarolinska Institutet
(författare)
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Svensson, ÅkeStockholms universitet,Matematiska institutionen(Swepub:su)akes
(författare)
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Hultcrantz, RolfKarolinska Institutet
(författare)
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Bäck, ErikÖrebro universitet,Hälsoakademin(Swepub:oru)ekbk
(författare)
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Ekdahl, Karl
(författare)
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Örebro universitetHälsoakademin
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:Journal of Viral Hepatitis: Wiley15:7, s. 538-5501352-05041365-2893
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