Occupational physical activity and renal cell cancer: a nationwide cohort study in Sweden

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Bergström, A.Karolinska Institutet (författare)

Occupational physical activity and renal cell cancer : a nationwide cohort study in Sweden

Artikel/kapitelEngelska1999

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New York, USA :John Wiley & Sons,1999
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LIBRIS-ID:oai:DiVA.org:oru-48972
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-48972URI
https://doi.org/10.1002/(sici)1097-0215(19991008)83:2<186::aid-ijc7>3.0.co;2-6DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:1943570URI

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Språk:engelska
Sammanfattning på:engelska

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Ämneskategori:art swepub-publicationtype

Anmärkningar

The causes of renal cell cancer remain incompletely understood. In one previous retrospective case-control study, high occupational physical activity has been associated with a decreased risk among men, but not among women. Our aim was to investigate the association between occupational physical activity and renal cell cancer in a large cohort in Sweden. A cohort of Swedish men and women was identified in the nationwide censuses in 1960 and 1970, and the reported occupations were classified into 4 levels of physical demands. Follow-up from 1971 through 1989 was accomplished through record linkages to the Swedish Cancer Registry. Multivariate Poisson regression models were used to estimate relative risk (RR) and 95% confidence intervals (CI). We found a monotonic increase in risk of renal cell cancer with decreasing level of occupational physical activity among men (p for trend <0.001). After adjustment for socio-economic status, place of residence, and calendar year of follow-up, men with long-term sedentary jobs had a 25% (RR = 1.25, 95% CI 1.02-1.53) increased risk compared to men with physically demanding occupations. Among women there was no association, the dose-risk trend was not significant (p for trend >0.50). Occupational physical activity was inversely associated with renal cell cancer among men. The absence of association among women might be due to smaller range of exposure, confounding by household work or reproductive factors, or to a difference in biological response to physical activity in men and women.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Cancer och onkologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Cancer and Oncology hsv//eng
Adult
Aged
Aged
80 and over
Carcinoma
Renal Cell/*epidemiology
Cohort Studies
Female
Humans
Kidney Neoplasms/*epidemiology
Male
Middle Aged
Occupational Diseases/*epidemiology
*Physical Exertion
Poisson Distribution
Risk Factors
Sweden/epidemiology

Biuppslag (personer, institutioner, konferenser, titlar ...)

Moradi, T.Karolinska Institutet (författare)
Lindblad, Per,1953-Department of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden; Department of Urology, Sundsvall Hospital, Sundsvall, Sweden(Swepub:oru)pld (författare)
Nyren, O.Karolinska Institutet (författare)
Adami, H. O.Karolinska Institutet (författare)
Wolk, A.Karolinska Institutet (författare)
Karolinska InstitutetDepartment of Medical Epidemiology, Karolinska Institutet, Stockholm, Sweden; Department of Urology, Sundsvall Hospital, Sundsvall, Sweden (creator_code:org_t)

Sammanhörande titlar

Ingår i:International Journal of CancerNew York, USA : John Wiley & Sons83:2, s. 186-910020-71361097-0215

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Av författaren/redakt...: Bergström, A.; Moradi, T.; Lindblad, Per, 1 ...; Nyren, O.; Adami, H. O.; Wolk, A.

Om ämnet

MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Cancer och onkol ...

Artiklar i publikationen: International Jo ...

Av lärosätet: Örebro universitet; Karolinska Institutet

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