Search: ((WFRF:(Li X.)) mspu:(researchreview)) srt2:(2015-2019) >
Dose-Response Relat...
Dose-Response Relationship between Dietary Magnesium Intake and Risk of Type 2 Diabetes Mellitus : A Systematic Review and Meta-Regression Analysis of Prospective Cohort Studies
-
- Fang, X. (author)
- Karolinska Institutet
-
- Han, H. (author)
- Department of Health Statistics, Second Military Medical University, Shanghai, China
-
- Li, M. (author)
- Department of Cardiology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China
-
show more...
-
- Liang, C. (author)
- Department of Cardiology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China
-
- Fan, Z. (author)
- Department of Cardiology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China
-
- Aaseth, J. (author)
- Kongsvinger Hospital Division, Innlandet Hospital Trust, Kongsvinger, Norway; Kongsvinger Hospital Division, Innlandet Hospital Trust, Kongsvinger, Norway
-
- He, J. (author)
- Department of Health Statistics, Second Military Medical University, Shanghai, China
-
- Montgomery, Scott, 1961- (author)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Clinical Epidemiology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden; Department of Epidemiology and Public Health, University College London, London, UK,Clinical Epidemiology and Biostatistics
-
- Cao, Yang, 1972- (author)
- Karolinska Institutet,Örebro universitet,Institutionen för medicinska vetenskaper,Unit of Biostatistics, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden,Clinical Epidemiology and Biostatistics
-
show less...
-
(creator_code:org_t)
- 2016-11-19
- 2016
- English.
-
In: Nutrients. - Basel, Switzerland : MDPIAG. - 2072-6643. ; 8:11
- Related links:
-
https://doi.org/10.3...
-
show more...
-
https://www.mdpi.com...
-
https://urn.kb.se/re...
-
https://doi.org/10.3...
-
http://kipublication...
-
show less...
Abstract
Subject headings
Close
- The epidemiological evidence for a dose-response relationship between magnesium intake and risk of type 2 diabetes mellitus (T2D) is sparse. The aim of the study was to summarize the evidence for the association of dietary magnesium intake with risk of T2D and evaluate the dose-response relationship. We conducted a systematic review and meta-analysis of prospective cohort studies that reported dietary magnesium intake and risk of incident T2D. We identified relevant studies by searching major scientific literature databases and grey literature resources from their inception to February 2016. We included cohort studies that provided risk ratios, i.e., relative risks (RRs), odds ratios (ORs) or hazard ratios (HRs), for T2D. Linear dose-response relationships were assessed using random-effects meta-regression. Potential nonlinear associations were evaluated using restricted cubic splines. A total of 25 studies met the eligibility criteria. These studies comprised 637,922 individuals including 26,828 with a T2D diagnosis. Compared with the lowest magnesium consumption group in the population, the risk of T2D was reduced by 17% across all the studies; 19% in women and 16% in men. A statistically significant linear dose-response relationship was found between incremental magnesium intake and T2D risk. After adjusting for age and body mass index, the risk of T2D incidence was reduced by 8%-13% for per 100 mg/day increment in dietary magnesium intake. There was no evidence to support a nonlinear dose-response relationship between dietary magnesium intake and T2D risk. The combined data supports a role for magnesium in reducing risk of T2D, with a statistically significant linear dose-response pattern within the reference dose range of dietary intake among Asian and US populations. The evidence from Europe and black people is limited and more prospective studies are needed for the two subgroups.
Subject headings
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Public Health, Global Health, Social Medicine and Epidemiology (hsv//eng)
- MEDICIN OCH HÄLSOVETENSKAP -- Hälsovetenskap -- Näringslära (hsv//swe)
- MEDICAL AND HEALTH SCIENCES -- Health Sciences -- Nutrition and Dietetics (hsv//eng)
Keyword
- magnesium; dietary intake; type 2 diabetes; prospective study; cohort study; meta-analysis
- Epidemiology
- Epidemiologi
- Näringslära
- Nutrition
Publication and Content Type
- ref (subject category)
- for (subject category)
Find in a library
-
Nutrients
(Search for host publication in LIBRIS)
To the university's database
- By the author/editor
-
Fang, X.
-
Han, H.
-
Li, M.
-
Liang, C.
-
Fan, Z.
-
Aaseth, J.
-
show more...
-
He, J.
-
Montgomery, Scot ...
-
Cao, Yang, 1972-
-
show less...
- About the subject
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Public Health Gl ...
-
- MEDICAL AND HEALTH SCIENCES
-
MEDICAL AND HEAL ...
-
and Health Sciences
-
and Nutrition and Di ...
- Articles in the publication
-
Nutrients
- By the university
-
Örebro University
-
Karolinska Institutet