Substance use disorders, psychiatric disorders, and mortality after release from prison: a nationwide longitudinal cohort study

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Chang, ZhengKarolinska Institutet (författare)

Substance use disorders, psychiatric disorders, and mortality after release from prison : a nationwide longitudinal cohort study

Artikel/kapitelEngelska2015

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Elsevier,2015
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LIBRIS-ID:oai:DiVA.org:oru-54497
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-54497URI
https://doi.org/10.1016/S2215-0366(15)00088-7DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:131236569URI

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Språk:engelska
Sammanfattning på:engelska

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BACKGROUND: High mortality rates have been reported in people released from prison compared with the general population. However, few studies have investigated potential risk factors associated with these high rates, especially psychiatric determinants. We aimed to investigate the association between psychiatric disorders and mortality in people released from prison in Sweden.METHODS: We studied all people who were imprisoned since Jan 1, 2000, and released before Dec 31, 2009, in Sweden for risks of all-cause and external-cause (accidents, suicide, homicide) mortality after prison release. We obtained data for substance use disorders and other psychiatric disorders, and criminological and sociodemographic factors from population-based registers. We calculated hazard ratios (HRs) by Cox regression, and then used them to calculate population attributable fractions for post-release mortality. To control for potential familial confounding, we compared individuals in the study with siblings who were also released from prison, but without psychiatric disorders. We tested whether any independent risk factors improved the prediction of mortality beyond age, sex, and criminal history.FINDINGS: We identified 47,326 individuals who were imprisoned. During a median follow-up time of 5·1 years (IQR 2·6-7·5), we recorded 2874 (6%) deaths after release from prison. The overall all-cause mortality rate was 1205 deaths per 100,000 person-years. Substance use disorders significantly increased the rate of all-cause mortality (alcohol use: adjusted HR 1·62, 95% CI 1·48-1·77; drug use: 1·67, 1·53-1·83), and the association was independent of sociodemographic, criminological, and familial factors. We identified no strong evidence that other psychiatric disorders increased mortality after we controlled for potential confounders. In people released from prison, 925 (34%) of all-cause deaths in men and 85 (50%) in women were potentially attributable to substance use disorders. Substance use disorders were also an independent determinant of external-cause mortality, with population attributable fraction estimates at 42% in men and 70% in women. Substance use disorders significantly improved the prediction of external-cause mortality, in addition to sociodemographic and criminological factors.INTERPRETATION: Interventions to address substance use disorders could substantially decrease the burden of excess mortality in people released from prison, but might need to be provided beyond the immediate period after release.

Ämnesord och genrebeteckningar

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Psykiatri hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Psychiatry hsv//eng
Psychiatry
Psykiatri

Biuppslag (personer, institutioner, konferenser, titlar ...)

Lichtenstein, PaulKarolinska Institutet (författare)
Larsson, Henrik,1975-Karolinska Institutet(Swepub:oru)hiln (författare)
Fazel, SeenaDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom (författare)
Karolinska InstitutetDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom (creator_code:org_t)

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Ingår i:Lancet psychiatry: Elsevier2:5, s. 422-4302215-03742215-0366

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Av författaren/redakt...: Chang, Zheng; Lichtenstein, Pa ...; Larsson, Henrik, ...; Fazel, Seena

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MEDICIN OCH HÄLSOVETENSKAP: MEDICIN OCH HÄLS ...; och Klinisk medicin; och Psykiatri

Artiklar i publikationen: Lancet psychiatr ...

Av lärosätet: Örebro universitet; Karolinska Institutet

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