Use of proton pump inhibitors and subsequent risk of celiac disease

↓ Direkt till sidans innehåll
↓ Direkt till sidans sekundära innehåll (sidomenyn)

Search: onr:"swepub:oai:DiVA.org:oru-56601" > Use of proton pump ...

1 of 1
Previous record
Next record
To hitlist

Details
MARC

Lebwohl, BenjaminColl Phys & Surg, Dept Med, Celiac Dis Ctr, Columbia Univ, New York NY, USA; Dept Med, Clin Epidemiol Unit, Karolinska Univ Hosp, Stockholm, Sweden; Karolinska Inst, Stockholm, Sweden (author)

Use of proton pump inhibitors and subsequent risk of celiac disease

Article/chapterEnglish2014

Publisher, publication year, extent ...

Elsevier BV,2014
printrdacarrier

Numbers

LIBRIS-ID:oai:DiVA.org:oru-56601
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-56601URI
https://doi.org/10.1016/j.dld.2013.08.128DOI
http://kipublications.ki.se/Default.aspx?queryparsed=id:128065993URI

Supplementary language notes

Language:English
Summary in:English

Part of subdatabase

SwePubSwePub

Classification

Subject category:ref swepub-contenttype
Subject category:art swepub-publicationtype

Notes

Background: The prevalence of celiac disease and the use of medications that inhibit acid secretion have both increased in recent decades. Aim: To explore the association between antisecretory medication exposure and subsequent development of celiac disease. Methods: In this population-based case control study, we identified patients with celiac disease diagnosed at all pathology departments in Sweden from July 2005 through February 2008. Patients were matched by age and gender with up to 5 controls. We identified prior prescriptions for proton pump inhibitors and histamine-2 receptor antagonists in all subjects. We used conditional logistic regression to measure the association between these prescriptions and the subsequent diagnosis of celiac disease. Results: Prior proton pump inhibitor prescription was strongly associated with celiac disease (OR 4.79; 95% CI 4.17-5.51). Patients prescribed both proton pump inhibitors and histamine-2 receptor antagonists had a higher risk of celiac disease (OR 5.96; 95% CI 3.58-9.91) than those prescribed proton pump inhibitors alone (OR 4.91; 95% CI 4.26-5.66) or histamine-2 receptor antagonists alone (OR 4.16; 95% CI 2.89-5.99). Conclusions: Exposure to antisecretory medications is associated with a subsequent diagnosis of celiac disease. The persistence of this association after excluding prescriptions in the year preceding the celiac disease diagnosis suggests a causal relationship. (C) 2013 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Subject headings and genre

MEDICIN OCH HÄLSOVETENSKAP Klinisk medicin Gastroenterologi hsv//swe
MEDICAL AND HEALTH SCIENCES Clinical Medicine Gastroenterology and Hepatology hsv//eng
Celiac disease
Proton pump inhibitors
Risk factors

Added entries (persons, corporate bodies, meetings, titles ...)

Spechler, Stuart J.Dept Internal Med, Div Gastroenterol, Department of Veterans Affairs North Texas Healthcare Syst, Dallas TX, USA; University of Texas Southwestern Med Ctr, Dallas TX, USA (author)
Wang, Timothy C.Coll Phys & Surg, Dept Med, Celiac Dis Ctr, Columbia Univ, New York NY, USA (author)
Green, Peter H. R.Coll Phys & Surg, Dept Med, Celiac Dis Ctr, Columbia Univ, New York NY, USA (author)
Ludvigsson, Jonas F.Karolinska Institutet,Region Örebro län,Dept Med, Clin Epidemiol Unit, Karolinska Univ Hosp, Stockholm, Sweden; Karolinska Inst, Stockholm, Sweden; Dept Pediat, Örebro Univ Hosp, Örebro, Sweden(Swepub:oru)jsln (author)
Coll Phys & Surg, Dept Med, Celiac Dis Ctr, Columbia Univ, New York NY, USA; Dept Med, Clin Epidemiol Unit, Karolinska Univ Hosp, Stockholm, Sweden; Karolinska Inst, Stockholm, SwedenDept Internal Med, Div Gastroenterol, Department of Veterans Affairs North Texas Healthcare Syst, Dallas TX, USA; University of Texas Southwestern Med Ctr, Dallas TX, USA (creator_code:org_t)

Related titles

In:Digestive and Liver Disease: Elsevier BV46:1, s. 36-401590-86581878-3562

Internet link

Find in a library

Digestive and Liver Disease (Search for host publication in LIBRIS)

To the university's database

1 of 1
Previous record
Next record
To hitlist

Find more in SwePub

By the author/editor: Lebwohl, Benjami ...; Spechler, Stuart ...; Wang, Timothy C.; Green, Peter H. ...; Ludvigsson, Jona ...

About the subject

MEDICAL AND HEALTH SCIENCES: MEDICAL AND HEAL ...; and Clinical Medicin ...; and Gastroenterology ...

Articles in the publication: Digestive and Li ...

By the university: Örebro University; Karolinska Institutet

Search outside SwePub

Extend your search to:: Google; Google Book Search; Google Scholar

Kungliga biblioteket hanterar dina personuppgifter i enlighet med EU:s dataskyddsförordning (2018), GDPR. Läs mer om hur det funkar här.
Så här hanterar KB dina uppgifter vid användning av denna tjänst.

LIBRIS.kb.se