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Dairy intake in rel...
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Downer, Mary K.Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston MA, United States; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston MA, United States; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston MA, United States
(författare)
Dairy intake in relation to prostate cancer survival
- Artikel/kapitelEngelska2017
Förlag, utgivningsår, omfång ...
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2017-02-22
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Hoboken :John Wiley & Sons,2017
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printrdacarrier
Nummerbeteckningar
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LIBRIS-ID:oai:DiVA.org:oru-57668
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-57668URI
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https://doi.org/10.1002/ijc.30642DOI
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https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-337254URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:135670155URI
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Språk:engelska
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Sammanfattning på:engelska
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Ämneskategori:ref swepub-contenttype
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Ämneskategori:art swepub-publicationtype
Anmärkningar
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Dairy intake has been associated with increased risk of advanced prostate cancer. Two US cohort studies reported increased prostate cancer-specific mortality with increased high-fat milk intake. We examined whether dairy and related nutrient intake were associated with prostate cancer progression in a Swedish patient population with high dairy consumption. We prospectively followed 525 men with newly diagnosed prostate cancer (diagnosed 1989-1994). We identified and confirmed deaths through February 2011 (n = 222 prostate cancer-specific, n = 268 from other causes). Cox proportional hazards regression was used to calculate hazard ratios (HR) and 95% confidence intervals (CI) for the associations between food or nutrient intake and prostate cancer-specific death. On average, patients consumed 5.0 servings/day of total dairy products at diagnosis. In the whole population, high-fat milk intake was not associated with prostate cancer-specific death (95% CI: 0.78, 2.10; p-trend = 0.32; multivariate-adjusted model). However, among patients diagnosed with localized prostate cancer, compared to men who consumed <1 servings/day of high-fat milk, those who drank >= 3 servings/day had an increased hazard of prostate cancer mortality (HR = 6.10; 95% CI: 2.14, 17.37; p-trend = 0.004; multivariate-adjusted model). Low-fat milk intake was associated with a borderline reduction in prostate cancer death among patients with localized prostate cancer. These associations were not observed among patients diagnosed with advanced stage prostate cancer. Our data suggest a positive association between high-fat milk intake and prostate cancer progression among patients diagnosed with localized prostate cancer. Further studies are warranted to investigate this association and elucidate the mechanisms by which high-fat milk intake may promote prostate cancer progression.
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Biuppslag (personer, institutioner, konferenser, titlar ...)
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Batista, Julie L.Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston MA, United States; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston MA, United States
(författare)
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Mucci, Lorelei A.Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston MA, United States; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston MA, United States
(författare)
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Stampfer, Meir J.
(författare)
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Epstein, Mara MeyerDepartment of Medicine and the Meyers Primary Care Institute, University of Massachusetts Medical School, Worcester MA, United States
(författare)
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Håkansson, NiclasKarolinska Institutet
(författare)
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Wolk, AlicjaKarolinska Institutet,Uppsala universitet,Ortopedi(Swepub:uu)alwol516
(författare)
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Johansson, Jan-Erik,1946-Region Örebro län,Department of Urology, Örebro University Hospital, Örebro, Sweden(Swepub:oru)jkjn
(författare)
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Andrén, Ove,1963-Region Örebro län,Department of Urology, Örebro University Hospital, Örebro, Sweden(Swepub:oru)oan
(författare)
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Fall, Katja,1971-Örebro universitet, Institutionen för medicinska vetenskaper,Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston MA, United States; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Urology, Örebro University Hospital, Örebro, Sweden(Swepub:oru)kafl
(författare)
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Andersson, Swen-Olof,1949-Region Örebro län,Department of Urology, Örebro University Hospital, Örebro, Sweden(Swepub:oru)sfan
(författare)
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Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston MA, United States; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston MA, United States; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston MA, United StatesDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston MA, United States; Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston MA, United States
(creator_code:org_t)
Sammanhörande titlar
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Ingår i:International Journal of CancerHoboken : John Wiley & Sons140:9, s. 2060-20690020-71361097-0215
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Downer, Mary K.
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Batista, Julie L ...
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Mucci, Lorelei A ...
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Stampfer, Meir J ...
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Epstein, Mara Me ...
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Håkansson, Nicla ...
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Wolk, Alicja
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Johansson, Jan-E ...
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Andrén, Ove, 196 ...
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Fall, Katja, 197 ...
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Andersson, Swen- ...
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