Sökning: id:"swepub:oai:DiVA.org:oru-61756" >
Ten years transmiss...
-
Dahlberg, JennyUppsala universitet,Klinisk mikrobiologi
(författare)
Ten years transmission of the new variant of Chlamydia trachomatis in Sweden : prevalence of infections and associated complications
- Artikel/kapitelEngelska2018
Förlag, utgivningsår, omfång ...
-
2017-07-19
-
BMJ Publishing Group Ltd,2018
-
printrdacarrier
Nummerbeteckningar
-
LIBRIS-ID:oai:DiVA.org:oru-61756
-
https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-61756URI
-
https://doi.org/10.1136/sextrans-2016-052992DOI
-
https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-343605URI
Kompletterande språkuppgifter
-
Språk:engelska
-
Sammanfattning på:engelska
Ingår i deldatabas
Klassifikation
-
Ämneskategori:ref swepub-contenttype
-
Ämneskategori:art swepub-publicationtype
Anmärkningar
-
Funding Agencies:Uppsala University Hospital Örebro County Council Research Committee Foundation for Medical Research at Örebro University Hospital, Sweden
-
OBJECTIVES: In 2006, a new variant of Chlamydia trachomatis (nvCT) was discovered in Sweden. It has a deletion in the plasmid resulting in failed detection by the single target systems from Abbott and Roche used at that time, whereas the third system used, from Becton Dickinson (BD), detects nvCT. The proportion of nvCT was initially up to 65% in counties using Abbott/Roche systems. This study analysed the proportion of nvCT from 2007 to 2015 in four selected counties and its impact on chlamydia-associated complications.METHODS: C. trachomatis-positive specimens collected from 2007 to 2015 were analysed by a specific PCR to identify nvCT cases. Genotyping was performed by multilocus sequence typing (MLST) and ompA sequencing. Ectopic pregnancy and pelvic inflammatory disease records were extracted from the national registers.RESULTS: In total, 5101 C. trachomatis-positive samples were analysed. The nvCT proportion significantly decreased in the two counties using Roche systems, from 56% in 2007 to 6.5% in 2015 (p<0.001). In the two counties using BD systems, a decrease was also seen, from 19% in 2007 to 5.2% in 2015 (p<0.001). Fifteen nvCT cases from 2015 and 102 cases from 2006 to 2009 had identical MLST profiles. Counties using Roche/Abbott systems showed higher mean rates of ectopic pregnancy and pelvic inflammatory disease compared with counties using BD systems.CONCLUSIONS: The nvCT proportion has decreased in all counties and converged to a low prevalence irrespective of previous rates. Genotyping showed that nvCT is clonal and genetically stable. Failing detection only marginally affected complication rates.
Ämnesord och genrebeteckningar
Biuppslag (personer, institutioner, konferenser, titlar ...)
-
Hadad, Ronza,1984-Örebro universitet,Institutionen för naturvetenskap och teknik,WHO Collaborating Centre for Gonorrhoea and other STIs, Örebro University Hospital, Örebro, Sweden(Swepub:oru)rahd
(författare)
-
Elfving, KarinDepartment of Clinical Microbiology, Falu Lasarett, Falun, Sweden
(författare)
-
Larsson, IngerDepartment of Clinical Microbiology, Sunderby Hospital, Luleå, Sweden
(författare)
-
Isaksson, JennyUppsala universitet,Klinisk mikrobiologi(Swepub:uu)jenis440
(författare)
-
Magnuson, AndersClinical Epidemiology and Biostatistics
(författare)
-
Fredlund, Hans,1952-WHO Collaborating Centre for Gonorrhoea and other STIs, Örebro University Hospital, Örebro, Sweden(Swepub:oru)hfd
(författare)
-
Unemo, Magnus,1970-WHO Collaborating Centre for Gonorrhoea and other STIs, Örebro University Hospital, Örebro, Sweden(Swepub:oru)muo
(författare)
-
Herrmann, Björn,1955-Uppsala universitet,Klinisk mikrobiologi(Swepub:uu)bjorherr
(författare)
-
Uppsala universitetKlinisk mikrobiologi
(creator_code:org_t)
Sammanhörande titlar
-
Ingår i:Sexually Transmitted Infections: BMJ Publishing Group Ltd94:2, s. 100-1041368-49731472-3263
Internetlänk
Hitta via bibliotek
Till lärosätets databas
- Av författaren/redakt...
-
Dahlberg, Jenny
-
Hadad, Ronza, 19 ...
-
Elfving, Karin
-
Larsson, Inger
-
Isaksson, Jenny
-
Magnuson, Anders
-
visa fler...
-
Fredlund, Hans, ...
-
Unemo, Magnus, 1 ...
-
Herrmann, Björn, ...
-
visa färre...
- Om ämnet
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Medicinska och f ...
-
och Mikrobiologi ino ...
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Infektionsmedici ...
-
- MEDICIN OCH HÄLSOVETENSKAP
-
MEDICIN OCH HÄLS ...
-
och Klinisk medicin
-
och Klinisk laborato ...
- Artiklar i publikationen
-
Sexually Transmi ...
- Av lärosätet
-
Örebro universitet
-
Uppsala universitet