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Search: (L773:1873 734X) mspu:(article) pers:(Mennander Ari) > Medium-term surviva...

  • Olsson, ChristianKarolinska Institutet (author)

Medium-term survival after surgery for acute Type A aortic dissection is improving

  • Article/chapterEnglish2017

Publisher, publication year, extent ...

  • 2017-09-18
  • Oxford University Press,2017
  • printrdacarrier

Numbers

  • LIBRIS-ID:oai:DiVA.org:oru-62455
  • https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-62455URI
  • https://doi.org/10.1093/ejcts/ezx302DOI
  • https://lup.lub.lu.se/record/4e55e69d-ffd8-4d93-bccc-417850edbd73URI
  • http://kipublications.ki.se/Default.aspx?queryparsed=id:136971822URI
  • https://gup.ub.gu.se/publication/260041URI

Supplementary language notes

  • Language:English
  • Summary in:English

Part of subdatabase

Classification

  • Subject category:ref swepub-contenttype
  • Subject category:art swepub-publicationtype

Notes

  • Funding agencies:Mats Kleberg Foundation 
  • OBJECTIVES: To report long-term survival and predictors of mortality in patients included in a large, contemporary, multicentre, multinational database: Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD), which consists of 8 centres in 4 Nordic countries.METHODS: Currently, NORCAAD includes 1159 patients operated between 2005 and 2014. In 30-day survivors (n = 955, 82%), the Kaplan-Meier and Cox proportional hazard methods were used to analyse medium-term (up to 8 years) survival and relative survival versus a matched normal population. Pre- and intraoperative predictors were expressed as hazard ratio (HR) with 95% confidence interval (95% CI).RESULTS: Cumulative follow-up was 3514 patient-years with a median of 3.2 years (range 0-10.2 years). Survival was 95% (95% CI 93-96) at 1 year, 86% (95% CI 83-88) at 5 years and 76% (95% CI 72-81) at 8 years. Relative survival versus a matched normal population was 95% (95% CI 94-97) at 1 year, 90% (95% CI 87-93) at 5 years and 85% (95% CI 80-90) at 8 years. In multivariable analysis, increased age (HR 1.05 per year, 95% CI 1.04-1.07), previous abdominal or thoracic aortic repair (HR 3.2, 95% CI 1.6-6.4) and chronic renal disease (HR 2.7, 95% CI 1.2-6.2) were associated with increased medium-term mortality. Open distal anastomosis (HR 0.55, 95% CI 0.35-0.87) and operation in the 2010-2014 period (HR 0.90, 95% CI 0.83-0.97) were associated with decreased medium-term mortality.CONCLUSIONS: Medium-term survival after acute Type A aortic dissection in the NORCAAD registry is satisfactory, close to a matched normal population and improved in the later part of the study period. The use of open distal anastomosis was associated with decreased medium-term mortality.

Subject headings and genre

Added entries (persons, corporate bodies, meetings, titles ...)

  • Ahlsson, Anders,1962-Karolinska Institutet (author)
  • Fuglsang, SimonDepartment of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark (author)
  • Geirsson, ArnarDepartment of Cardiothoracic Surgery, Faculty of Medicine, Landspitali University Hospital, University of Iceland, Reykjavik, Iceland,National University Hospital of Iceland (author)
  • Gunn, JarmoDepartment of Cardiothoracic Surgery, Turku University Hospital, Turku, Finland (author)
  • Hansson, Emma C.,1985Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xhanem (author)
  • Hjortdal, VibekeDepartment of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark (author)
  • Jarvela, KatiDepartment of Cardiothoracic Surgery, Heart Center Tampere University Hospital, Tampere, Finland (author)
  • Jeppsson, Anders,1960Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xjepan (author)
  • Mennander, AriDepartment of Cardiothoracic Surgery, Heart Center Tampere University Hospital, Tampere, Finland (author)
  • Nozohoor, ShahabLund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Minimalinvasiv hjärtkirurgi vid hjärtklaffsjukdom,Forskargrupper vid Lunds universitet,Blödningsrubbningar och akut typ-A dissektion,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Minimal invasive cardiac surgery in valvular heart disease,Lund University Research Groups,Bleeding disorders and acute typ-A dissection,Skåne University Hospital(Swepub:lu)med-snh (author)
  • Wickbom, Anders,1987-Department of Cardiothoracic and Vascular Surgery, Orebro University Hospital, Orebro, Sweden(Swepub:oru)aswm (author)
  • Zindovic, IgorLund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Minimalinvasiv hjärtkirurgi vid hjärtklaffsjukdom,Forskargrupper vid Lunds universitet,Blödningsrubbningar och akut typ-A dissektion,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Minimal invasive cardiac surgery in valvular heart disease,Lund University Research Groups,Bleeding disorders and acute typ-A dissection,Skåne University Hospital(Swepub:lu)med-izn (author)
  • Gudbjartsson, TomasDepartment of Cardiothoracic Surgery, Faculty of Medicine, Landspitali University Hospital, University of Iceland, Reykjavik, Iceland,National University Hospital of Iceland (author)
  • Karolinska InstitutetDepartment of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark (creator_code:org_t)

Related titles

  • In:European Journal of Cardio-Thoracic Surgery: Oxford University Press52:5, s. 852-8571010-79401873-734X

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