Search: (L773:1873 734X) mspu:(article) pers:(Mennander Ari) >
Medium-term surviva...
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Olsson, ChristianKarolinska Institutet
(author)
Medium-term survival after surgery for acute Type A aortic dissection is improving
- Article/chapterEnglish2017
Publisher, publication year, extent ...
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2017-09-18
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Oxford University Press,2017
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printrdacarrier
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LIBRIS-ID:oai:DiVA.org:oru-62455
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https://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-62455URI
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https://doi.org/10.1093/ejcts/ezx302DOI
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https://lup.lub.lu.se/record/4e55e69d-ffd8-4d93-bccc-417850edbd73URI
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http://kipublications.ki.se/Default.aspx?queryparsed=id:136971822URI
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https://gup.ub.gu.se/publication/260041URI
Supplementary language notes
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Language:English
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Summary in:English
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Subject category:ref swepub-contenttype
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Subject category:art swepub-publicationtype
Notes
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Funding agencies:Mats Kleberg Foundation
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OBJECTIVES: To report long-term survival and predictors of mortality in patients included in a large, contemporary, multicentre, multinational database: Nordic Consortium for Acute Type A Aortic Dissection (NORCAAD), which consists of 8 centres in 4 Nordic countries.METHODS: Currently, NORCAAD includes 1159 patients operated between 2005 and 2014. In 30-day survivors (n = 955, 82%), the Kaplan-Meier and Cox proportional hazard methods were used to analyse medium-term (up to 8 years) survival and relative survival versus a matched normal population. Pre- and intraoperative predictors were expressed as hazard ratio (HR) with 95% confidence interval (95% CI).RESULTS: Cumulative follow-up was 3514 patient-years with a median of 3.2 years (range 0-10.2 years). Survival was 95% (95% CI 93-96) at 1 year, 86% (95% CI 83-88) at 5 years and 76% (95% CI 72-81) at 8 years. Relative survival versus a matched normal population was 95% (95% CI 94-97) at 1 year, 90% (95% CI 87-93) at 5 years and 85% (95% CI 80-90) at 8 years. In multivariable analysis, increased age (HR 1.05 per year, 95% CI 1.04-1.07), previous abdominal or thoracic aortic repair (HR 3.2, 95% CI 1.6-6.4) and chronic renal disease (HR 2.7, 95% CI 1.2-6.2) were associated with increased medium-term mortality. Open distal anastomosis (HR 0.55, 95% CI 0.35-0.87) and operation in the 2010-2014 period (HR 0.90, 95% CI 0.83-0.97) were associated with decreased medium-term mortality.CONCLUSIONS: Medium-term survival after acute Type A aortic dissection in the NORCAAD registry is satisfactory, close to a matched normal population and improved in the later part of the study period. The use of open distal anastomosis was associated with decreased medium-term mortality.
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Ahlsson, Anders,1962-Karolinska Institutet
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Fuglsang, SimonDepartment of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark
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Geirsson, ArnarDepartment of Cardiothoracic Surgery, Faculty of Medicine, Landspitali University Hospital, University of Iceland, Reykjavik, Iceland,National University Hospital of Iceland
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Gunn, JarmoDepartment of Cardiothoracic Surgery, Turku University Hospital, Turku, Finland
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Hansson, Emma C.,1985Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xhanem
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Hjortdal, VibekeDepartment of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark
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Jarvela, KatiDepartment of Cardiothoracic Surgery, Heart Center Tampere University Hospital, Tampere, Finland
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Jeppsson, Anders,1960Gothenburg University,Göteborgs universitet,Institutionen för medicin, avdelningen för molekylär och klinisk medicin,Institute of Medicine, Department of Molecular and Clinical Medicine(Swepub:gu)xjepan
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Mennander, AriDepartment of Cardiothoracic Surgery, Heart Center Tampere University Hospital, Tampere, Finland
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Nozohoor, ShahabLund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Minimalinvasiv hjärtkirurgi vid hjärtklaffsjukdom,Forskargrupper vid Lunds universitet,Blödningsrubbningar och akut typ-A dissektion,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Minimal invasive cardiac surgery in valvular heart disease,Lund University Research Groups,Bleeding disorders and acute typ-A dissection,Skåne University Hospital(Swepub:lu)med-snh
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Wickbom, Anders,1987-Department of Cardiothoracic and Vascular Surgery, Orebro University Hospital, Orebro, Sweden(Swepub:oru)aswm
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Zindovic, IgorLund University,Lunds universitet,Thoraxkirurgi,Sektion II,Institutionen för kliniska vetenskaper, Lund,Medicinska fakulteten,Minimalinvasiv hjärtkirurgi vid hjärtklaffsjukdom,Forskargrupper vid Lunds universitet,Blödningsrubbningar och akut typ-A dissektion,Thoracic Surgery,Section II,Department of Clinical Sciences, Lund,Faculty of Medicine,Minimal invasive cardiac surgery in valvular heart disease,Lund University Research Groups,Bleeding disorders and acute typ-A dissection,Skåne University Hospital(Swepub:lu)med-izn
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Gudbjartsson, TomasDepartment of Cardiothoracic Surgery, Faculty of Medicine, Landspitali University Hospital, University of Iceland, Reykjavik, Iceland,National University Hospital of Iceland
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Karolinska InstitutetDepartment of Cardiothoracic and Vascular Surgery, Aarhus University Hospital, Skejby, Denmark
(creator_code:org_t)
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In:European Journal of Cardio-Thoracic Surgery: Oxford University Press52:5, s. 852-8571010-79401873-734X
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Olsson, Christia ...
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Ahlsson, Anders, ...
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Fuglsang, Simon
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Geirsson, Arnar
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Gunn, Jarmo
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Hjortdal, Vibeke
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Jarvela, Kati
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Nozohoor, Shahab
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Zindovic, Igor
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Örebro University
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